本文選題：nm準(zhǔn)分子光 + nm高能窄譜LED紫外線　； 參考：《臨床皮膚科雜志》2017年12期

【摘要】：目的:對比分析308 nm準(zhǔn)分子光和308 nm高能窄譜發(fā)光二極管(LED)紫外線治療白癜風(fēng)的臨床療效差異及安全性。方法:選擇不同臨床類型的白癜風(fēng)患者76例,共246處色素脫失斑,每例患者選擇相近或?qū)ΨQ部位的皮損隨機(jī)分組,一組皮損進(jìn)行308 nm準(zhǔn)分子光治療,對應(yīng)的另一組皮損進(jìn)行308 nm高能窄譜LED紫外線治療。每周治療二三次,連續(xù)治療20次。觀察、記錄療效及不良反應(yīng)。結(jié)果:治療20次后,308 nm準(zhǔn)分子光組的有效率為50.41%,308 nm高能窄譜LED紫外線組的有效率為52.03%,兩組差異無統(tǒng)計(jì)學(xué)意義(P0.05)。隨著治療次數(shù)的增加,兩組患者的治療有效率均有顯著增加(P0.05)。兩組患者不同部位皮損療效差異均有統(tǒng)計(jì)學(xué)意義(P0.05),其中面頸部的療效均優(yōu)于其他部位,軀干和四肢的療效優(yōu)于肢端。結(jié)論:308 nm準(zhǔn)分子光和308 nm高能窄譜LED紫外線治療白癜風(fēng)的臨床療效均安全有效。
[Abstract]:Objective: to compare the clinical efficacy and safety of 308 nm excimer light and 308 nm high energy narrow spectrum light emitting diode (LED) in the treatment of vitiligo. Methods: 76 patients with vitiligo of different clinical types, 246 spots of pigment loss were selected. Each patient was randomly divided into two groups with similar or symmetrical lesions. One group of lesions was treated with 308 nm excimer light. Another group of skin lesions was treated with 308nm high energy narrow spectrum LED ultraviolet radiation. Two or three times a week, 20 consecutive times. Observe and record curative effect and adverse reaction. Results: after 20 times of treatment, the effective rate of 308nm excimer group was 50.41nm and 308nm high energy narrow spectrum LED ultraviolet group was 52.03.The difference between the two groups was not statistically significant (P 0.05). With the increase of treatment times, the effective rate of treatment was significantly increased in both groups (P 0.05). There were significant differences in skin lesions between the two groups (P 0.05). The curative effect of face and neck was better than that of other parts, and the curative effect of trunk and extremities was better than that of extremities. Conclusion it is safe and effective to treat vitiligo with 1: 308 nm excimer light and 308 nm high energy narrow spectrum LED ultraviolet rays.
【作者單位】： 中山大學(xué)附屬第八醫(yī)院皮膚科;
【分類號】：R758.41

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1 龔洋洋;光綜合療法治療難治性白癜風(fēng)初步研究[D];北京協(xié)和醫(yī)學(xué)院;2017年

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本文編號：1912319