本文選題：表皮囊腫 + 癌��； 參考：《天津醫(yī)藥》2014年08期

【摘要】：目的探討表皮樣囊腫癌變的臨床特點(diǎn)、病理形態(tài)、免疫組化及預(yù)后等。方法收集6例表皮樣囊腫癌變資料,分析其臨床特點(diǎn),觀察病理形態(tài)及免疫組化表型,通過(guò)隨訪了解其預(yù)后。結(jié)果臨床表現(xiàn)均為局部包塊,行擴(kuò)大切除,隨訪1年,無(wú)復(fù)發(fā)和轉(zhuǎn)移。病理檢查示為不整形腫塊,囊性,內(nèi)為豆渣樣物,鏡檢示囊內(nèi)為變性層狀角質(zhì)物,囊壁襯覆鱗狀上皮,癌變區(qū)鱗狀上皮呈巢團(tuán)狀間質(zhì)浸潤(rùn)。病理診斷表皮樣囊腫癌變?yōu)轺[狀細(xì)胞癌。免疫表型:6例癌變鱗狀細(xì)胞CK5/6、P63陽(yáng)性。結(jié)論表皮樣囊腫癌變非常少見(jiàn),診斷主要靠常規(guī)病理切片確診,免疫組化標(biāo)記協(xié)助診斷,局部適當(dāng)擴(kuò)大切除為首選,其惡性程度較低,預(yù)后較好。
[Abstract]:Objective to investigate the clinical features, pathological morphology, immunohistochemistry and prognosis of epidermoid cyst carcinogenesis. Methods six cases of epidermoid cysts with carcinogenesis were collected, their clinical features, histopathology and immunohistochemical phenotype were observed. Results all the clinical manifestations were local mass, extended resection, followed up for 1 year, no recurrence or metastasis. Pathological examination showed no plastic mass, cystic and soybean dregs. Microscopic examination showed denatured layered keratinocytes in the capsule, squamous epithelium lining the cystic wall and nestled interstitial infiltration in the cancerous area. Pathological diagnosis of carcinogenesis of epidermoid cyst to squamous cell carcinoma. Immunophenotypes: 6 cases of malignant squamous cell CK5 / 6 p63 positive. Conclusion Carcinogenesis of epidermoid cysts is rare. The diagnosis is mainly confirmed by conventional pathological sections, with the help of immunohistochemical markers, and local excision is the first choice. The malignant degree is lower and the prognosis is better.
【作者單位】： 新疆阿克蘇市農(nóng)一師醫(yī)院病理科;新疆阿克蘇市農(nóng)一師醫(yī)院理療科;
【分類號(hào)】：R739.5

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本文編號(hào)：1821788