外泌體與皮膚科相關(guān)疾病的研究進(jìn)展
發(fā)布時(shí)間:2018-04-29 16:57
本文選題:外泌體 + 皮膚科; 參考:《臨床皮膚科雜志》2017年05期
【摘要】:外泌體是一種可由大多數(shù)種類細(xì)胞分泌的納米級(jí)(直徑30~100 nm)囊泡。它不僅是細(xì)胞的代謝產(chǎn)物,而且具有在細(xì)胞間傳遞信息的生物學(xué)功能,可以通過(guò)內(nèi)吞作用、微胞飲作用甚至直接與細(xì)胞膜脂質(zhì)融合等機(jī)制被受體細(xì)胞攝取。目前有研究發(fā)現(xiàn),外泌體與變態(tài)反應(yīng)性疾病、黑素瘤、自身免疫性疾病及傷口愈合等皮膚相關(guān)的疾病有很大關(guān)系,在各種生理和病理過(guò)程中發(fā)揮著重要的生物學(xué)作用。該文對(duì)外泌體與皮膚科相關(guān)疾病的研究進(jìn)展作一綜述。
[Abstract]:Exocrine is a nanoscale (30 ~ 100 nm in diameter) vesicle that can be secreted by most kinds of cells. It is not only the metabolite of cells, but also has the biological function of transmitting information between cells. It can be ingested by receptor cells through endocytosis, microcytosis and even direct fusion with cell membrane lipid. At present, it has been found that the exocrine body is closely related to allergic diseases, melanoma, autoimmune diseases, wound healing and other skin related diseases, and plays an important biological role in various physiological and pathological processes. This article reviews the research progress of external secretion and dermatology related diseases.
【作者單位】: 南京醫(yī)科大學(xué)附屬無(wú)錫人民醫(yī)院皮膚科;南京醫(yī)科大學(xué)附屬無(wú)錫二院皮膚科;南京醫(yī)科大學(xué)第一附屬醫(yī)院皮膚科;
【分類號(hào)】:R751
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本文編號(hào):1820789
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