本文選題：止癬方 + 復方十一烯酸鋅曲安奈德軟膏�。� 參考：《成都中醫(yī)藥大學》2012年碩士論文

【摘要】：目的：通過對60例混合型足癬患者隨機采用“止癬方聯(lián)合新腳氣膏”或“足光粉聯(lián)合新腳氣膏”治療的臨床觀察,研究兩種方法治療手足癬的主要療效、有效率、真菌清除率、瘙癢程度、皮膚光滑度、復發(fā)率、安全性。同時初步探求一種中西結合治療足癬的方法。 方法：將符合本次研究病例納入標準的60例足癬患者,隨機分為治療組(30例)和對照組(30例)。其中治療組患者采用止癬方聯(lián)合新腳氣膏治療,對照組患者采用足光粉聯(lián)合新腳氣膏治療,兩組均治療4周,治療結束后2周(即第6周)、3個月后隨訪,觀察兩組治療前后、近期、遠期臨床療效。 結果：經過對足癬患者的治療及隨訪,治療組和對照組治療4周結束后主要療效分別為46.67%、36.67%,顯效率分別為73.33%、46.67%,真菌清除率分別為63.33%、76.67%；治療結束后2周主要療效分別為53.33%、36.67%,顯效率分別為76.67%、53.33%,真菌清除率分別為66.67%、76.67%。經統(tǒng)計分析,兩組間治療結束時、結束后2周主要療效無明顯差異(p0.05)；顯效率有顯著差異(pO.05),治療組痊愈率優(yōu)于對照組；真菌清除率無明顯差異(pO.05),對照組略高于治療組；兩組治療4周結束后以及治療結束后2周的癥狀體征總積分相比有顯著差異,其中瘙癢程度和皮膚光滑程度均有差異。說明對于混合型足癬的治療,實驗組近期療效優(yōu)于對照組；兩組復發(fā)率比較無明顯差異；實驗組的起效快于對照組,癥狀改善優(yōu)于對照組,皮損修復好于對照組。 結論：對混合型足癬的治療,止癬方聯(lián)合復方十一烯酸鋅曲安奈德軟膏療效確切、近期療效好、復發(fā)率低,值得臨床進行進一步研究與推廣
[Abstract]:Objective: to study the main curative effect, effective rate and fungal clearance rate of 60 patients with mixed tinea pedis treated by "Zhi tinea prescription combined with new beriberi ointment" or "foot powder combined with new tibia cream". Pruritus degree, skin smoothness, recurrence rate, safety. At the same time, a combination of Chinese and Western treatment of tinea pedis was preliminarily explored. Methods: 60 patients with tinea pedis were randomly divided into treatment group (n = 30) and control group (n = 30). The patients in the treatment group were treated with tinea prescription combined with new tibia ointment, and the patients in the control group were treated with foot light powder combined with new beriberi ointment. The patients in both groups were treated for 4 weeks, 2 weeks after the end of treatment (i.e., 6 weeks, 3 months later), and observed before and after treatment. Short-term, long-term clinical effect. Results: after the treatment and follow-up of patients with tinea pedis, The main curative effects of the treatment group and the control group were 46.67 and 36.67 respectively after the end of 4 weeks of treatment, the significant effective rates were 73.33 and 46.67, respectively, and the fungous clearance rates were 63.33 and 76.67, respectively, and the main curative effects were 53.33 and 36.67, respectively, at 2 weeks after the end of the treatment, the significant effective rates were 76.67 and 53.33, respectively, and the fungal clearance rates were respectively 66.67 and 76.677.In the second week after the treatment, the main curative effects were 76.67 and 53.33, and the fungal clearance rates were respectively 66.67 and 76.67 in the two weeks after the treatment. At the end of the treatment, there was no significant difference in the main curative effect between the two groups at the end of treatment (p0.05), significant difference in the effective rate was found between the two groups, the cure rate in the treatment group was better than that in the control group, and there was no significant difference in the fungal clearance rate between the two groups, which was slightly higher in the control group than in the treatment group. There were significant differences in the total score of symptoms and signs between the two groups after 4 weeks of treatment and 2 weeks after treatment, including the degree of pruritus and the degree of skin smoothness. For the treatment of mixed tinea pedis, the short-term efficacy of the experimental group is better than that of the control group; there is no significant difference in the recurrence rate between the two groups. Conclusion: for the treatment of mixed tinea pedis, the compound zinctriamcinolone undecenoate ointment is effective and has good short-term effect and low recurrence rate. It is worthy of further clinical study and popularization.
【學位授予單位】：成都中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R756

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