本文選題：脂溢性脫發(fā) + 代謝綜合征��； 參考：《廣州中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：1.本研究檢測不同年齡段脂溢性脫發(fā)(AGA)患者的空腹血糖、TG,、TC、HDL-C、 LDL-C、腰圍、BMI、血壓等代謝綜合征(Ms)相關(guān)指標(biāo),以探討脂溢性脫發(fā)與Ms的相關(guān)性。2.本研究觀測脂溢性脫發(fā)不同脫發(fā)等級及中醫(yī)證型與空腹血糖、TG、TC、 HDL-C、 LDL-C,腰圍、BMI、血壓等MS相關(guān)指標(biāo)的相關(guān)性,以期為臨床防治AGA患者發(fā)生Ms提供一些思路。方法：本研究共納入脂溢性脫發(fā)患者168例,健康體檢者170例。檢測兩組空腹血糖、TG、TC、 HDL-C、 LDL-C、腰圍、BMI、血壓等Ms相關(guān)指標(biāo),并進(jìn)行統(tǒng)計(jì)分析。結(jié)果：1.脂溢性脫發(fā)患者合并代謝綜合征的有12例(7.14%),健康體檢者合并代謝綜合征的有4例(2.35%),脂溢性脫發(fā)患者合并代謝綜合征的概率較健康體檢者的明顯升高,差異具有顯著性。2.本研究所納入168例脂溢性脫發(fā)患者中有明確家族史的69例,占41.07%。3.廣東地區(qū)20-25歲、26-30歲、31-35歲3個年齡段脂溢性脫發(fā)患者的空腹Tc、LDL-C水平及異常率均明顯高于健康體檢者,差異具有顯著性。4.廣東地區(qū)脂溢性脫發(fā)患者脫發(fā)等級按Hamilton-Norwood scale標(biāo)準(zhǔn)進(jìn)行分組,其中Ⅱ級有60人,占35.71%,Ⅲ級有57人,占33.93%,Ⅳ級有51人,占30.36%。年齡對TC、LDL-C影響較少或無影響,而脫發(fā)等級與TC、LDL-C呈正相關(guān)關(guān)系,脫發(fā)等級越高,發(fā)生MS的風(fēng)險(xiǎn)越高。5.廣東地區(qū)脂溢性脫發(fā)患者的中醫(yī)證型以肝腎不足證為主,占41.67%；而濕熱內(nèi)蘊(yùn)證及血虛風(fēng)燥證分別為35.71%、22.62%。不同中醫(yī)證型脂溢性脫發(fā)患者的MS相關(guān)指標(biāo)存在差異,濕熱內(nèi)蘊(yùn)證脂溢性脫發(fā)患者Tc、HDL-C水平及異常率均明顯高于肝腎不足證及血虛風(fēng)燥證,濕熱內(nèi)蘊(yùn)可能是導(dǎo)致脂溢性脫發(fā)患者發(fā)生代謝綜合征的促發(fā)因素之一。結(jié)論：1.廣東地區(qū)脂溢性脫發(fā)患者可能容易發(fā)生代謝綜合征,患者空腹TC、LDL-C的水平及異常率均明顯高于相同年齡段的健康體檢者。2.廣東地區(qū)不同脫發(fā)等級脂溢性脫發(fā)患者M(jìn)S相關(guān)指標(biāo)存在差異,年齡對TC、LDL-C影響較少或無影響,而脫發(fā)等級與TC、LDL-C呈正相關(guān)關(guān)系,脫發(fā)等級越高,發(fā)生MS的風(fēng)險(xiǎn)越高。3.廣東地區(qū)脂溢性脫發(fā)患者中醫(yī)辨證分型比例從高到低依次是肝腎不足證、濕熱內(nèi)蘊(yùn)證、血虛風(fēng)燥證。不同中醫(yī)證型脂溢性脫發(fā)患者M(jìn)S相關(guān)指標(biāo)存在差異,濕熱內(nèi)蘊(yùn)證脂溢性脫發(fā)患者Tc、HDL-C水平及異常率明顯高于肝腎不足證及血虛風(fēng)燥證,濕熱內(nèi)蘊(yùn)可能是導(dǎo)致脂溢性脫發(fā)患者發(fā)生代謝綜合征的促發(fā)因素之一。
[Abstract]:Purpose 1. In order to explore the correlation between seborrheic alopecia and Ms, the study examined the related indexes of fasting blood glucose (TGG), TCU (HDL-C, LDL-C), waist circumference (BMI) and blood pressure (BP) in patients with seborrheic alopecia (AGAA) in different age groups, in order to explore the correlation between seborrheic alopecia and Ms. In this study, we observed the correlation between different grades of seborrheic alopecia and TCM syndromes and MS related indexes such as TGG TC, HDL-C, LDL-C, waist circumference BMIand blood pressure, etc, in order to provide some ideas for clinical prevention and treatment of AGA patients. Methods: 168 patients with seborrheic alopecia and 170 healthy persons were enrolled in this study. Ms related indexes such as TGG, HDL-C, LDL-C, BMI, blood pressure and so on were detected and statistically analyzed in the two groups. The result is 1: 1. There were 12 cases of seborrheic alopecia complicated with metabolic syndrome and 4 cases of healthy check-up with metabolic syndrome. The probability of seborrheic alopecia complicated with metabolic syndrome was significantly higher than that of healthy person (P < 0.05). 69 of 168 seborrheic alopecia patients (41.07%) had a family history. The fasting Tc LDL-C level and abnormal rate of seborrheic alopecia patients aged 20-25 years old from 26 to 30 years old were significantly higher than those of healthy controls (P < 0.05). The hair loss grade of seborrheic alopecia patients in Guangdong area was divided into groups according to Hamilton-Norwood scale standard. Among them, there were 60 cases in grade 鈪，

本文編號：1786137