本文選題：原發(fā)性手汗癥 + 流行病學(xué)��； 參考：《揚州大學(xué)》2017年碩士論文

【摘要】：目的:原發(fā)性多汗癥是一種身體汗液分泌過度超出機(jī)體正常需要量為特征的疾病,一般不存在器質(zhì)性病因,出汗部位以手掌、足底、顱面部和腋窩多見。根據(jù)機(jī)體出汗增多部位可分為原發(fā)性手汗癥、原發(fā)性頭汗癥、原發(fā)性腋汗癥等。目前已有部分文獻(xiàn)報告了原發(fā)性手汗癥相關(guān)流行病學(xué)資料,在我國全國范圍內(nèi)已經(jīng)進(jìn)行了一項針對青少年原發(fā)性手汗癥的流行病學(xué)調(diào)查。本次調(diào)查研究的目的旨在針對揚州地區(qū)青少年進(jìn)行相關(guān)調(diào)查研究,以了解揚州地區(qū)青少年人群中原發(fā)性手汗癥的患病率及相關(guān)因素。方法:1.調(diào)查研究前,確定調(diào)查對象,設(shè)計調(diào)查問卷,對所有參與調(diào)查的人員進(jìn)行專門培訓(xùn),明確相關(guān)手汗癥診斷標(biāo)準(zhǔn)及注意事項。2.正式調(diào)查前,在小范圍內(nèi)抽取樣本進(jìn)行預(yù)調(diào)查,驗證調(diào)查方法、調(diào)查問卷的可行性和可信度。3.采用隨機(jī)抽樣,以班級為單位隨機(jī)抽取揚州地區(qū)大中學(xué)校各兩所部分班級全部學(xué)生進(jìn)行現(xiàn)場問卷調(diào)查。并且向每個學(xué)生交代調(diào)查目的、意義、及問卷填寫方式,取得其知情同意。調(diào)查人員將問卷分發(fā)給在校學(xué)生,現(xiàn)場指導(dǎo)其填寫問卷,填寫完整后問卷由調(diào)查人員統(tǒng)一收回。錄入調(diào)查數(shù)據(jù),根據(jù)診斷標(biāo)準(zhǔn)篩選出其中可疑手汗癥患者,再由專門人員對疑似患者進(jìn)行問診,以排除其他疾病繼發(fā)手掌出汗增多,并作出診斷和嚴(yán)重程度分級。4.結(jié)合問卷調(diào)查資料及診斷,匯總調(diào)查資料,對其進(jìn)行統(tǒng)計整理,分析原發(fā)性手汗癥患病率及相關(guān)因素,得出實驗結(jié)論。結(jié)果:本次調(diào)查研究共隨機(jī)抽取揚州地區(qū)青少年3504例,其中男性1577例,女性1927例,根據(jù)診斷標(biāo)準(zhǔn)篩選出手汗癥患者共107例,原發(fā)性手汗癥的患病率為3.05%。男性患病率為3.87%(61例/1577例),女性患病率為2.39%(46例/1927例),男性患病率高于女性。初中生905例,患病率3.00%;高中生785例,患病率2.97%;大學(xué)生1927例,患病率3.12%,各就學(xué)階段手汗癥患病率差異無統(tǒng)計學(xué)意義。首次發(fā)病年齡主要集中于10-20歲(73.56%)。男性手汗癥患病率高于女性,但嚴(yán)重手汗癥患者中女性數(shù)量多于男性。原發(fā)性手汗癥患者常常伴隨足底、腋窩等部位出汗增多,且女性更容易存在除手掌以外身體其他部位多汗。36.45%的患者有家族史,病變嚴(yán)重者其家族遺傳傾向更加明顯。結(jié)論:揚州地區(qū)青少年手汗癥患病率為3.05%,男性患病率高于女性,患者常于青少年時期發(fā)病,存在一定程度的性別差異,常合并身體其他部位多汗癥狀,且具有較為明顯的遺傳傾向。
[Abstract]:Objective: primary hyperhidrosis is a disease characterized by excessive secretion of sweat over the normal amount of body. There is generally no organic etiology and perspiration is common in palm, plantar, craniofacial and axillary.According to the site of hyperhidrosis can be divided into primary palmar hyperhidrosis, primary head sweat, primary axillary hyperhidrosis and so on.At present, some literatures have reported the epidemiological data of primary palmar sweatosis, and an epidemiological survey has been carried out in China.The purpose of this study is to investigate the prevalence and related factors of primary palmar sweat in young people in Yangzhou.Method 1: 1.Before investigation and research, determine the survey object, design the questionnaire, conduct special training for all the personnel involved in the investigation, and clarify the diagnostic criteria and precautions of the related palmar hyperhidrosis. 2.Before the formal investigation, samples are collected in a small area for pre-investigation to verify the survey method, the feasibility and credibility of the questionnaire. 3.Random sampling was used to select randomly all the students in each of the two middle and high schools in Yangzhou.And to explain to each student the purpose, significance, and manner of filling the questionnaire, to obtain their informed consent.The questionnaire was distributed to the students and instructed them to fill out the questionnaire.Input the survey data, screen out the suspected palmar sweat patients according to the diagnostic criteria, and then examine the suspected patients by specialized personnel to exclude the increase of palmar sweating secondary to other diseases, and make the diagnosis and severity grade. 4.Based on the data of questionnaire and diagnosis, the data of investigation were collected, and the prevalence rate of primary palmar sweat and related factors were analyzed, and the experimental results were obtained.Results: a total of 3504 adolescents in Yangzhou were randomly selected, including 1577 males and 1927 females. According to the diagnostic criteria, 107 cases of palmar sweat were selected. The prevalence rate of primary palmar hyperhidrosis was 3.05%.The prevalence rate of male was 3.87 / 1577 and that of female was 2.399.46 / 1927. The prevalence of male was higher than that of female.There were 905 junior high school students with a prevalence rate of 3.00; 785 high school students with a prevalence rate of 2.97; 1927 college students with a prevalence rate of 3.122.There was no significant difference in the prevalence of palmar hyperhidrosis in each stage of schooling.The age of the first onset was mainly in the age of 10-20 years old.The prevalence of palmar hyperhidrosis in males is higher than that in females, but the number of females in patients with severe palms is higher than that in males.Patients with primary palmar hyperhidrosis were often accompanied by increased sweating in the plantar, armpit and other parts, and women were more likely to have a family history of sweating in other parts of the body other than the palms, and the family genetic tendency was more obvious if the lesions were serious.Conclusion: the prevalence of palmar hyperhidrosis is 3.05 in Yangzhou area, the prevalence rate of male is higher than that of female, the patients often develop in adolescence, there is a certain degree of gender difference, often combined with hyperhidrosis in other parts of body.And has obvious genetic tendency.
【學(xué)位授予單位】：揚州大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R758.74
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本文編號：1745786