抑郁癥狀對(duì)尖銳濕疣患者生活質(zhì)量的影響
發(fā)布時(shí)間:2018-03-29 20:44
本文選題:尖銳濕疣 切入點(diǎn):生活質(zhì)量 出處:《鄭州大學(xué)》2012年碩士論文
【摘要】:背景與目的 目前,隨著生物-心理-醫(yī)學(xué)模式的日趨成熟,心理健康越來越受到人們的關(guān)注,心理干預(yù)也逐步應(yīng)用于臨床治療,并取得良好的效果。尖銳濕疣(condyloma acuminata, CA)患者作為一個(gè)特殊的人群,其心理問題不容忽視。該病臨床增生快,易復(fù)發(fā),部分還有發(fā)生癌變的可能,患者往往存在不同程度的心理障礙,生活質(zhì)量普遍下降,抑郁癥狀在臨床較為常見。嚴(yán)重的心理應(yīng)激與機(jī)體的免疫功能存在廣泛的交互影響,導(dǎo)致機(jī)體免疫功能的低下,進(jìn)而可促進(jìn)疣體的復(fù)發(fā)。本文通過對(duì)CA患者的抑郁癥狀及生活質(zhì)量進(jìn)行調(diào)查,分析患者抑郁及生活質(zhì)量的影響因素,并進(jìn)一步探討抑郁癥狀與生活質(zhì)量之間的關(guān)系,為臨床實(shí)施心理干預(yù),提高患者生活質(zhì)量和療效提供理論依據(jù)。 方法 2010年3月至2011年6月鄭州大學(xué)第一附屬醫(yī)院皮膚科門診治療的170例CA患者作為研究組,對(duì)照組為170例健康者。研究組和對(duì)照組均采用Zung抑郁自評(píng)量表(self-rating depression scale, SDS)、皮膚科生活質(zhì)量指數(shù)(dermatology life quality index, DLQI)進(jìn)行問卷調(diào)查,并用自制調(diào)查表采集一般情況。研究組SDS≥0.5者作為抑郁組,SDS0.5者作為非抑郁組。利用SPSS17.0統(tǒng)計(jì)軟件對(duì)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)學(xué)分析,定性資料的比較采用χ2檢驗(yàn),定量資料的比較采用t檢驗(yàn)及單因素方差分析。各相關(guān)因素與生活質(zhì)量的關(guān)系采用單因素相關(guān)分析和多元回歸,檢驗(yàn)水準(zhǔn)α=0.05。 結(jié)果 1.研究組中抑郁的發(fā)生率明顯高于對(duì)照組(47.5%vs26.6%),且抑郁的發(fā)生與經(jīng)濟(jì)狀況、婚姻、病程、對(duì)疾病的認(rèn)識(shí)、文化程度、自覺癥狀、初次就診情況相關(guān)(P0.05),與性別、年齡無關(guān)(P0.05)。 2.研究組生活質(zhì)量總分明顯高于對(duì)照組(12.72±2.02vs7.83±1.11),且與性別、經(jīng)濟(jì)狀況、婚姻、病程、對(duì)疾病的認(rèn)識(shí)、文化程度、自覺癥狀、初次就診情況、抑郁癥狀相關(guān)(P0.05),與年齡無關(guān)(P0.05)。 3.抑郁癥狀與生活質(zhì)量呈正相關(guān)(r=0.718,P0.001),研究組中抑郁組的生活質(zhì)量總分明顯高于非抑郁組(14.35±1.65vs11.31±1.17,t=13.389),且抑郁程度與生活質(zhì)量總分相關(guān)。 結(jié)論 1.CA患者抑郁癥狀發(fā)生率高,并導(dǎo)致生活質(zhì)量下降; 2.經(jīng)濟(jì)狀況、婚姻、病程、對(duì)疾病的認(rèn)識(shí)、文化程度、自覺癥狀、初次就診情況等因素均是患者抑郁癥狀的影響因素,而患者的抑郁癥狀、婚姻、病程、對(duì)疾病的認(rèn)識(shí)及初次就診情況是生活質(zhì)量的危險(xiǎn)因素。
[Abstract]:Background and purposeAt present, with the maturity of biological-psychological-medical model, people pay more and more attention to mental health. Psychological intervention has been gradually applied to clinical treatment and achieved good results.As a special group, condyloma acuminata (CAA) patients have psychological problems that can not be ignored.The clinical hyperplasia of the disease is fast, easy to recur, and part of the disease has the possibility of canceration. Patients often have different degrees of psychological disorders, the quality of life is generally decreased, and depressive symptoms are more common in clinical practice.Serious psychological stress and immune function of the body have extensive interaction, resulting in low immune function of the body, which can promote the recurrence of warts.By investigating the depression symptoms and quality of life of CA patients, this paper analyzed the influencing factors of depression and quality of life, and further discussed the relationship between depression symptoms and quality of life, so as to carry out psychological intervention in clinic.To improve the quality of life and efficacy of patients to provide theoretical basis.MethodFrom March 2010 to June 2011, 170 CA patients were treated in Department of Dermatology, first affiliated Hospital of Zhengzhou University as study group and 170 healthy persons as control group.Both the study group and the control group were investigated with self-rating depression scale (Zung) and dermatology life quality (DLQI).The study group with SDS 鈮,
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