本文選題：鱉甲煎丸　切入點(diǎn)：血熱型尋常型銀屑病　出處：《中成藥》2017年10期

【摘要】：目的探討鱉甲煎丸聯(lián)合西藥治療血熱型尋常型銀屑病的療效觀察。方法 2015年1月—2016年1月,共收治128例中老年血熱型尋常型銀屑病患者,隨機(jī)(數(shù)字隨機(jī)分組法)分為兩組,對(duì)照組采用西醫(yī)常規(guī)療法,觀察組在西醫(yī)常規(guī)療法的基礎(chǔ)上,采用鱉甲煎丸進(jìn)行治療。觀察和比較患者的治療效果、不良反應(yīng)、免疫調(diào)節(jié)作用、PASI(皮損面積及嚴(yán)重性指數(shù))評(píng)分。結(jié)果與對(duì)照組(78.13%)對(duì)比,觀察組治療有效率(98.44%)明顯更高,數(shù)據(jù)差異顯著,具有統(tǒng)計(jì)學(xué)意義(P0.05)。與治療前對(duì)比,觀察組治療1、2、3個(gè)月的PASI分明顯降低,對(duì)照組治療2個(gè)月、3個(gè)月的PASI分明顯降低,數(shù)據(jù)差異顯著,具有統(tǒng)計(jì)學(xué)意義(P0.05)。與對(duì)照組對(duì)比,觀察組治療1、2、3個(gè)月的PASI分明顯更低,數(shù)據(jù)差異顯著,具有統(tǒng)計(jì)學(xué)意義(P0.05)。與治療前對(duì)比,兩組CD4+明顯降低,CD4+/CD8+明顯上升,數(shù)據(jù)比較差異具有統(tǒng)計(jì)學(xué)意義,P0.05;與對(duì)照組對(duì)比,兩組治療后CD4+和CD4+/CD8+比較差異不具有統(tǒng)計(jì)學(xué)意義(P0.05)。與對(duì)照組(20.31%)對(duì)比,觀察組不良反應(yīng)發(fā)生率(7.81%)明顯更低,數(shù)據(jù)比較差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論基于西醫(yī)常規(guī)療法鱉甲煎丸治療血熱型尋常型銀屑病的療效顯著,不良反應(yīng)少,能夠有效地提高患者的免疫能力,安全性良好。
[Abstract]:Objective to observe the curative effect of Biejia Jian Pill combined with western medicine in treating psoriasis vulgaris of blood fever type. Methods A total of 128 cases of psoriasis vulgaris of blood fever type were treated from January 2015 to January 2016. They were randomly divided into two groups. The control group was treated with routine western medicine, while the observation group was treated with Biejia Jian Pill on the basis of western medicine routine therapy. The therapeutic effects and adverse reactions of the patients were observed and compared. Results compared with the control group (78.13), the effective rate of treatment in the observation group was significantly higher than that in the control group (P 0.05), and the difference was significant (P 0.05). The PASI score of the observation group was significantly lower than that of the control group for 2 months and the PASI score for 3 months. The difference was significant (P 0.05). Compared with the control group, the PASI score of the observation group was significantly lower than that of the control group, and the PASI score of the observation group was significantly lower than that of the control group. The difference was statistically significant (P 0.05). Compared with the control group, CD4 in the two groups decreased significantly the CD4 / CD8 ratio increased significantly, the difference was statistically significant (P0.05), and compared with the control group, there was no significant difference between the two groups. There was no significant difference in CD4 and CD4 / CD8 between the two groups after treatment. Compared with the control group (20.31), the incidence of adverse reactions in the observation group was significantly lower than that in the control group (7.81%). Conclusion Biejia Jian Pill, based on routine western medicine therapy, has significant curative effect and fewer adverse reactions in the treatment of blood-heat type psoriasis vulgaris. It can effectively improve the immune ability of the patients and has good safety.
【作者單位】： 湖北省黃石市鄂東醫(yī)療集團(tuán)中醫(yī)醫(yī)院;
【分類號(hào)】：R758.63
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本文編號(hào)：1663198