本文選題：威爾尼克外瓶霉　切入點(diǎn)：掌黑癬　出處：《臨床皮膚科雜志》2016年10期 　論文類型：期刊論文

【摘要】：報(bào)告1例威爾尼克外瓶霉致掌黑癬�；颊吲�,24歲。右手大魚際淡褐色橢圓形斑塊4年余,無不適。皮損鱗屑真菌鏡檢:10%KOH涂片可見淺棕色短菌絲及出芽孢子,美藍(lán)涂片染色可見短菌絲及孢子。皮屑培養(yǎng)生長(zhǎng)緩慢,初期為灰白色至橄欖色酵母樣菌落,很快變?yōu)槟G色至黑色菌落。菌落表面可見絮狀、暗灰色至綠灰色氣生菌絲。對(duì)培養(yǎng)菌株行土豆培養(yǎng)基小培養(yǎng)觀察形態(tài)學(xué)符合威爾尼克外瓶霉,用掃描電鏡觀察其產(chǎn)孢方式為環(huán)痕產(chǎn)孢、合軸式排列方式,菌絲兩側(cè)及頂端有環(huán)痕梗,環(huán)孢子聚集在環(huán)痕梗周圍�；驕y(cè)序與標(biāo)準(zhǔn)菌株GQ334387.1(GI:254802560)威爾尼克外瓶霉具有100%同源性。診斷為掌黑癬。給予5%硝酸舍他康唑乳膏每日2次外用,連用2周后皮損完全消退。隨訪3個(gè)月未見復(fù)發(fā)。
[Abstract]:A case of Meloderma palmaris caused by Vernique was reported. The patient was 24 years old. Her right hand was light brown oval plaques at the thenar margin for more than 4 years without discomfort. The smear of scaly fungi of skin lesions showed light brown short hyphae and sprouting spores by microscopic examination of 10 Koh smears. Short mycelium and spores can be seen in methylene blue smear. The growth of dander is slow. The initial colony is grayish white to olive yeast-like, and quickly becomes dark green to black colony. The surface of the colony is flocculent. Dark gray to green gray aerial hyphae. The microculture morphology of potato medium was in accord with Verniella Wilnique. The sporulation was observed by scanning electron microscope (SEM) in the form of ring mark sporulation and axonal arrangement. There were ringed stalks on both sides and top of hyphae, and the ring spores were gathered around the ring stripe. The gene sequence was 100% homology with standard strain GQ334387.1 and Gi: 254802560. It was diagnosed as tinea melangularis. 5% sertaconazole cream was given for external use twice a day. The lesions disappeared completely after 2 weeks of continuous use. No recurrence was found after 3 months of follow-up.
【作者單位】： 第四軍醫(yī)大學(xué)西京皮膚醫(yī)院;
【分類號(hào)】：R756.3
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本文編號(hào)：1611810