發(fā)布時(shí)間：2019-04-01 20:55

【摘要】：目的評(píng)估2型糖尿病患者血清25-羥維生素D3[25(OH)D3]水平與代謝的關(guān)系。方法選擇2014年6月至2015年6月于我院內(nèi)分泌科住院的遼寧省地區(qū)2型糖尿病患者254例,根據(jù)血清25(OH)D3測(cè)定時(shí)間將所有患者分為A組(1~5月和12月)和B組(6~11月),比較2組25(OH)D3、糖化血紅蛋白、空腹血糖等代謝指標(biāo),另外根據(jù)血清25(OH)D3水平將A、B 2組各分為4個(gè)亞組:A1組和B1組,25(OH)D3≥30 ng/m L;A2組和B2組,25(OH)D3為20~30 ng/m L;A3組和B3組,25(OH)D3為10~20ng/m L;A4組和B4組,25(OH)D310 ng/m L。比較各亞組相關(guān)代謝指標(biāo)。結(jié)果 B組血清25(OH)D3水平高于A組(P0.001)。A3組糖化血紅蛋白低于A4組(P=0.043)。A組和B組以及各個(gè)亞組間血鈣差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論遼寧省地區(qū)的2型糖尿病患者維生素D水平普遍較低,冬春季較夏秋季更顯著。遼寧省地區(qū)2型糖尿病患者需要補(bǔ)充維生素D,增加戶外運(yùn)動(dòng)。2型糖尿病患者維生素D缺乏與血糖水平有關(guān)。血清鈣不能作為評(píng)估維生素D的指標(biāo)。
[Abstract]:Objective to evaluate the relationship between serum 25-hydroxyvitamin D _ 3 [25 (OH) D _ 3] and metabolism in patients with type 2 diabetes mellitus. Methods from June 2014 to June 2015, 254 patients with type 2 diabetes mellitus in Liaoning province were divided into two groups: group A (1 ~ 5 months and 12 months) and group B (6 ~ 11 months) according to the time of serum 25 (OH) D3 determination. The metabolic indexes such as 25 (OH) D 3, glycosylated hemoglobin and fasting blood glucose were compared between the two groups. In addition, A and B 2 groups were divided into four subgroups according to the level of serum 25 (OH) D3: group A1 and group B1, 25 (OH) D3 鈮，

本文編號(hào)：2451901