甘南藏族人群鹽敏感性與代謝綜合征的關(guān)系研究
發(fā)布時間:2018-11-18 19:05
【摘要】:目的探討甘南藏族人群鹽敏感性(SS)與代謝綜合征(MS)的關(guān)系。方法于2013年6月—2014年11月,在甘肅省甘南藏族自治州夏河縣和合作縣選取原發(fā)性高血壓病1級者737例、非高血壓者631例。收集受試者的性別、年齡、身高、體質(zhì)量、腰圍、臀圍、血壓、空腹血糖(FPG)、三酰甘油(TG)、高密度脂蛋白膽固醇(HDL-C)等臨床資料,并計算BMI。采用我國改良后的急性鹽負荷試驗方法,根據(jù)Sullivan標準判定是否存在SS;分別根據(jù)中華醫(yī)學(xué)會糖尿病學(xué)分會(CDS)、國際糖尿病聯(lián)盟(IDF)、美國國家膽固醇教育計劃成人治療組第三次報告(NCEP-ATPⅢ)制定的診斷標準,判定是否患MS。結(jié)果甘南藏族高血壓者、非高血壓者的SS檢出率分別為72.9%(537/737)、64.5%(407/631),高血壓者高于非高血壓者,差異有統(tǒng)計學(xué)意義(P0.05)。根據(jù)CDS、IDF、NCEP-ATPⅢ診斷標準,高血壓者的MS檢出率分別為47.9%(353/737)、55.0%(405/737)、37.7%(278/737),非高血壓者的MS檢出率分別為3.5%(22/631)、15.8%(100/631)、4.8%(30/631)。是否存在SS高血壓者、非高血壓者根據(jù)CDS、IDF、NCEP-ATPⅢ的MS檢出率比較,差異均無統(tǒng)計學(xué)意義(P0.05)。SS高血壓者根據(jù)CDS的BMI偏高、根據(jù)NCEP-ATPⅢ的腰圍偏高檢出率低于非SS高血壓者,差異有統(tǒng)計學(xué)意義(P0.05);SS非高血壓者TG偏高、根據(jù)CDS的血糖偏高、根據(jù)IDF的血糖偏高、根據(jù)NCEP-ATPⅢ的血糖偏高檢出率低于非SS非高血壓者,根據(jù)IDF的腰圍偏高、根據(jù)NCEP-ATPⅢ的腰圍偏高檢出率高于非SS非高血壓者,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論甘南藏族高血壓人群和非高血壓人群的SS、MS檢出率均較高,SS與MS間無直接關(guān)系,但MS部分組分與SS間存在統(tǒng)計學(xué)關(guān)聯(lián),需進一步研究證實。
[Abstract]:Objective to investigate the relationship between salt-sensitive (SS) and metabolic syndrome (MS) in Gannan Tibetan population. Methods from June 2013 to November 2014, 737 cases of grade 1 essential hypertension and 631 cases of non-hypertension were selected from Xiahe County and Hehe County, Gansu Autonomous Prefecture of Gansu Province. The clinical data of sex, age, height, body mass, waist circumference, hip circumference, blood pressure, fasting blood glucose, (FPG), triacylglycerol, (TG), high density lipoprotein cholesterol (HDL-C) were collected, and BMI. was calculated. The modified acute salt load test method was used to determine the existence of SS; according to the Sullivan standard. According to the diagnostic criteria established by the third report (NCEP-ATP 鈪,
本文編號:2340907
[Abstract]:Objective to investigate the relationship between salt-sensitive (SS) and metabolic syndrome (MS) in Gannan Tibetan population. Methods from June 2013 to November 2014, 737 cases of grade 1 essential hypertension and 631 cases of non-hypertension were selected from Xiahe County and Hehe County, Gansu Autonomous Prefecture of Gansu Province. The clinical data of sex, age, height, body mass, waist circumference, hip circumference, blood pressure, fasting blood glucose, (FPG), triacylglycerol, (TG), high density lipoprotein cholesterol (HDL-C) were collected, and BMI. was calculated. The modified acute salt load test method was used to determine the existence of SS; according to the Sullivan standard. According to the diagnostic criteria established by the third report (NCEP-ATP 鈪,
本文編號:2340907
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