發(fā)布時間：2018-04-29 03:35

  本文選題：唾液腺顯像 + 定量分析��； 參考：《中國醫(yī)學(xué)影像技術(shù)》2017年03期

【摘要】：目的探討唾液腺顯像診斷干燥綜合征的價值。方法回顧性分析44例臨床懷疑干燥綜合征(SS)患者的唾液腺顯像資料,在雙側(cè)腮腺、頜下腺勾畫ROI獲得時間-放射性曲線(TAC),對曲線進(jìn)行定量分析獲得唾液腺攝取指數(shù)(UI)和排泌分?jǐn)?shù)(EF),分析UI和EF與唾液腺顯像定性分級診斷結(jié)果的相關(guān)性,并比較其診斷SS的效能。結(jié)果與非SS患者相比較,SS患者唾液腺UI和EF均明顯減低(P均0.05)。定性診斷評價唾液腺功能受損程度分為0~3級,雙側(cè)頜下腺、腮腺UI與定性診斷分級呈負(fù)相關(guān)(P均0.001);除右側(cè)頜下腺EF與唾液腺顯像定性分級呈負(fù)相關(guān)外(r=-0.312,P=0.039),其余腺體EF與定性診斷分級無相關(guān)性(P均0.05)。UI的綜合診斷效能均高于定性診斷,但是其ROC曲線下面積與定性診斷比較差異無統(tǒng)計學(xué)意義(P均0.05)。結(jié)論唾液腺顯像定量分析可準(zhǔn)確評價唾液腺功能,對診斷SS具有重要價值。
[Abstract]:Objective to evaluate the value of salivary gland imaging in the diagnosis of Sjogren's syndrome. Methods the imaging data of salivary glands in 44 patients with suspected Sjogren's syndrome (SSSS) were analyzed retrospectively. The ROI acquisition time-radioactivity curve was drawn. The salivary gland uptake index (UI) and excretion fraction (EFI) were obtained by quantitative analysis of the curves. The correlation between UI and EF was analyzed and compared with the diagnostic results of salivary gland imaging. Results the UI and EF of salivary glands in SS patients were significantly lower than those in non SS patients (P < 0.05). The degree of damage to salivary gland function was assessed by qualitative diagnosis and was divided into 3 grades: bilateral submandibular gland, submandibular gland, and submandibular gland. Except for the right submandibular gland EF and salivary gland imaging grade, there was a negative correlation between EF and salivary gland imaging grade. The comprehensive diagnostic efficacy of 0.05).UI was higher than that of qualitative diagnosis in all the patients with no correlation between EF and qualitative diagnostic grade of parotid gland (P = 0.001), except for the right submandibular gland (EF) and salivary gland imaging grade (P < 0.05), except for the right submandibular gland (EF) and salivary gland imaging grade (P < 0.05). However, there was no significant difference between the area under the ROC curve and the qualitative diagnosis (P = 0.05). Conclusion quantitative analysis of salivary gland imaging can accurately evaluate salivary gland function and has important value in the diagnosis of SS.
【作者單位】： 蘇州科技城醫(yī)院核醫(yī)學(xué)科;蘇州大學(xué)附屬第二醫(yī)院核醫(yī)學(xué)科;
【分類號】：R593.2

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