本文選題：糖尿病周圍神經(jīng)病變　切入點(diǎn)：宣痹通絡(luò)湯　出處：《新疆醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的:觀察宣痹通絡(luò)湯加減治療糖尿病周圍神經(jīng)病變痰瘀阻絡(luò)證的臨床療效。方法:本研究是臨床療效研究,將72例研究對象分為對照組35例和治療組37例,兩組均予基礎(chǔ)治療,另對照組予甲鈷胺片治療,治療組在對照組的基礎(chǔ)上加用宣痹通絡(luò)湯口服。治療8周后比較兩組治療前后震動感覺閾值(VPT)、踝肱指數(shù)(ABI)、中醫(yī)證候積分、多倫多臨床評分(TCSS)等指標(biāo)的變化,評價(jià)宣痹通絡(luò)湯的療效。結(jié)果:(1)VPT:兩組治療后治療組左右足VPT的改善優(yōu)于對照組(P0.05)。(2)ABI:兩組治療后治療組左右腿ABI的改善與對照組相比差異無統(tǒng)計(jì)學(xué)意義(P0.05)。(3)中醫(yī)證候積分:兩組治療后與治療前相比中醫(yī)證候積分均明顯下降(P0.05),組間比較肢體麻木、頭身困重、倦怠乏力三個(gè)癥狀積分改善治療組優(yōu)于對照組(P0.05)。(4)中醫(yī)癥狀綜合療效:治療組總有效率為81.1%,對照組為62.9%,治療組總有效率優(yōu)于對照組(P0.05)。(5)TCSS:治療后組間比較,治療組癥狀評分、TCSS總分的下降優(yōu)于對照組(P0.05)。結(jié)論:宣痹通絡(luò)湯聯(lián)合甲鈷胺片治療DPN在改善中醫(yī)證候積分、TCSS、VPT方面療效優(yōu)于單純甲鈷胺片治療。
[Abstract]:Objective: to observe the clinical effect of Xuanbi Tongluo decoction on phlegm and blood stasis syndrome of diabetic peripheral neuropathy.Methods: 72 cases were divided into control group (n = 35) and treatment group (n = 37). Both groups were treated with basic treatment, the control group were treated with mecobalamin tablets, the treatment group was treated with Xuantongbi decoction on the basis of the control group.After 8 weeks of treatment, the changes of vibration sensation threshold, ankle brachial index (ABI), TCM syndromes score, Toronto clinical score and TCSSwere compared between the two groups before and after treatment, and the curative effect of Xuanbi Tongluo decoction was evaluated.Results: after treatment, the improvement of left and right foot VPT in the treatment group was better than that in the control group (P 0.05). There was no significant difference between the treatment group and the control group in the improvement of left and right leg ABI.Compared with TCM syndromes, the scores of TCM syndromes decreased significantly (P 0.05), and the limbs were numb between groups.The total score of TCSS in the treatment group was lower than that in the control group (P 0.05).Conclusion: Xuanbi Tongluo decoction combined with mecobalamin tablet is superior to mecobalamin tablets in the treatment of DPN.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R587.2

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