本文選題：真實世界　切入點：人類免疫缺陷病毒　出處：《中國中西醫(yī)結(jié)合雜志》2017年04期

【摘要】：目的分析真實世界人類免疫缺陷病毒(human immunodeficiency virus,HIV)感染患者臨床特征及用藥規(guī)律。方法基于醫(yī)院信息系統(tǒng)(hospital information system,HIS)真實世界數(shù)據(jù),提取2006年1月—2011年12月全國17家三甲醫(yī)院HIV感染者病歷資料,包括患者一般信息、疾病特征及入院期間中西藥臨床應(yīng)用情況。結(jié)果共收集451例HIV感染者資料,有年齡記錄者261例,平均36歲,其中以18~65歲居多[90.4%(236/261)];男女比例為2.8∶1;HIV患者最常入住的科室為傳染病科[66.96%(302/451)],其次為呼吸科[8.2%(37/451)]�；颊呷朐悍绞揭蚤T診為主[79.6%(359/451)],其中以急診方式入院占20.18%(91/451)�；颊叨嘁蚋腥拘约膊∽≡�,其中以結(jié)核病最多(8.29%),其次為細菌性肺炎(6.44%)。349例有完整用藥記錄,共使用西藥399種,中成藥80種�？刮⑸锼幨褂妙l率最高(11.86%),以復方磺胺甲VA唑最多(2.81%)。80種中成藥以清熱解毒劑最常用(19.27%),其次為解表劑(10.30%)、補益劑(8.97%)、祛痰劑(7.31%)。抗微生物藥聯(lián)合清熱解毒劑是最常見的中西藥組合。451例HIV感染者經(jīng)中西藥治療,病情穩(wěn)定,好轉(zhuǎn)率達51.2%。結(jié)論 HIV感染患者中使用頻率最高西藥是抗微生物類藥,使用頻率最高中成藥為清熱類藥物。抗微生物藥與清熱解毒類中成藥聯(lián)合應(yīng)用在臨床上也較為常見。
[Abstract]:Objective to analyze the clinical characteristics and drug use patterns of patients infected with human immunodeficiency virus (immunodeficiency) virus in real world. Methods based on the real world data of hospital information system, From January 2006 to December 2011, the medical records of HIV infected patients in 17 third-class hospitals in China were collected, including general information of patients, disease characteristics and clinical application of Chinese and western medicine during admission. Results 451 cases of HIV infected patients were collected. There were 261 cases with an average of 36 years of age. Most of them were 180-65 years old [90.4 / 236 / 261]; the most common department for HIV patients with HIV was 2.88: 1; the department of infectious diseases [66.96 / 302451], followed by the respiratory department [8.2+ 37 / 451]. The mode of admission of patients was mainly outpatient [79.663 / 359451], of which 20.1891% were admitted to the emergency department. Most of the patients were hospitalized because of infectious diseases. Among them, most of them were tuberculosis (8.29%), followed by bacterial pneumonia (6.4444). 349 cases had complete drug records, totally 399 kinds of western medicine were used. There are 80 kinds of Chinese patent medicine. The antimicrobial drug is the most frequently used, and the compound sulfamethazol is the most common one, and the most common one is the antipyretic and detoxifying agent, followed by the antipyretic agent (10.30), the tonifying agent (8.97), the expectorant (7.31). The antimicrobial agent combined with the antipyretic detoxification agent is the most commonly used. Is the most common combination of Chinese and western medicine. 451 cases of HIV infected by Chinese and western medicine treatment, Conclusion the antimicrobial drugs are the most frequently used in patients with HIV infection. The antimicrobial and antipyretic drugs combined with antipyretic and detoxifying drugs are also common in clinic.
【作者單位】： 中國中醫(yī)科學院中醫(yī)臨床基礎(chǔ)醫(yī)學研究所;北京大學口腔醫(yī)學院口腔黏膜科;中國人民大學統(tǒng)計學院;
【基金】：國家科技重大專項項目(No.2009ZX09502-030)
【分類號】：R512.91
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本文編號：1665478