本文關鍵詞： 糖尿病足潰瘍 超聲清創(chuàng)刀 負壓創(chuàng)面　出處：《重慶醫(yī)學》2016年35期 　論文類型：期刊論文

【摘要】：目的探討使用超聲清創(chuàng)刀聯合負壓創(chuàng)面治療糖尿病足潰瘍的臨床療效。方法選取2014年6月至2015年6月在該院接受治療的70例糖尿病足潰瘍患者,根據隨機數字表法將其分為觀察組和對照組,各35例。對照組給予常規(guī)清創(chuàng)聯合負壓創(chuàng)面治療,觀察組采用超聲清創(chuàng)刀聯合負壓創(chuàng)面治療,比較兩組患者的治療效果。結果觀察組治療總有效率(94.28%)高于對照組(62.86%),差異有統(tǒng)計學意義(P0.05)。術前兩組血糖及糖化血紅蛋白(HbA1c)水平比較,差異均無統(tǒng)計學意義(P0.05);治療后,兩組患者術后血糖及HbA1c水平均較術前降低,且觀察組血糖及HbA1c水平均低于對照組,差異均有統(tǒng)計學意義(P0.05)。與對照組比較,治療后觀察組患者潰瘍面積減小,肉芽覆蓋率及潰瘍復發(fā)率降低,差異均有統(tǒng)計學意義(P0.05);但兩組截肢率及病死率比較,差異均無統(tǒng)計學意義(P0.05)。結論應用超聲清創(chuàng)刀聯合負壓創(chuàng)面治療糖尿病足潰瘍能明顯提高臨床療效,減小患者足部創(chuàng)面潰瘍面積,增加肉芽覆蓋率,有效降低潰瘍復發(fā)率,提高患者的生活質量。
[Abstract]:Objective to investigate the clinical effect of a clear knife combined with negative pressure wound treatment of diabetic foot ulcer with ultrasound. Methods 70 cases of diabetic foot ulcer patients from June 2014 to June 2015 in our hospital for treatment, then randomly divided into observation group and control group, 35 cases in each group. The control group was given routine debridement and wound treatment the negative pressure, the observation group with ultrasonic debridement knife combined with negative pressure wound therapy, compared two groups of patients. Results the total effective rate of the observation group (94.28%) was higher than the control group (62.86%), the difference was statistically significant (P0.05). The two groups preoperative blood glucose and glycosylated hemoglobin (HbA1c) level, there was no difference statistical significance (P0.05); after treatment, the two groups of patients with blood glucose and HbA1c levels were decreased, and the observation group blood glucose and HbA1c levels were lower than the control group, the differences were statistically significant (P0.05) compared with control group. After treatment, patients in the observation group, the ulcer area decreases, the coverage rate and the recurrence rate of ulcer granulation decreased, the differences were statistically significant (P0.05); but the amputation rate and mortality rate of two groups, there were no significant differences (P0.05). Conclusion the application of ultrasonic debridement knife combined with negative pressure wound treatment of diabetic foot ulcer can significantly improve the clinical curative effect, reduce the patient foot ulcer area, increase granulation coverage, reduce the recurrence rate of ulcer, improve the quality of life of patients.

【作者單位】： 河北省保定市第一醫(yī)院血管外科;河北省保定市第一醫(yī)院介入醫(yī)學科;
【分類號】：R587.2

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