本文關(guān)鍵詞： 糖尿病足 肌電圖 腓神經(jīng)　出處：《安徽醫(yī)科大學(xué)學(xué)報》2017年05期 　論文類型：期刊論文

【摘要】：目的分析糖尿病足潰瘍患者和未發(fā)生糖尿病足的2型糖尿病患者的肌電圖腓神經(jīng)傳導(dǎo)速度的差異及其影響因素。方法收集54例住院糖尿病足患者和54例住院不伴有糖尿病足的2型糖尿病患者的資料,回顧性分析這108例患者的臨床資料,研究糖尿病足潰瘍患者和未發(fā)生糖尿病足的2型糖尿病患者的肌電圖腓神經(jīng)傳導(dǎo)速度的差異及其影響因素。結(jié)果糖尿病足組與對照組相比,雙下肢肌電圖腓神經(jīng)傳導(dǎo)速度較慢,差異有統(tǒng)計學(xué)意義(P0.05)。兩組患者在受教育程度、白細(xì)胞計數(shù)、中性粒細(xì)胞比例、血紅蛋白、白蛋白、踝肱指數(shù)(ABI)方面差異有統(tǒng)計學(xué)意義(P0.05)。腓神經(jīng)感覺神經(jīng)傳導(dǎo)速度與糖化血紅蛋白、白細(xì)胞計數(shù)、中性粒細(xì)胞比例呈負(fù)相關(guān)性(P0.05);與空腹C肽水平、血紅蛋白、白蛋白及ABI呈正相關(guān)性(P0.05)。腓神經(jīng)運(yùn)動神經(jīng)傳導(dǎo)速度與吸煙時間、糖化血紅蛋白、中性粒細(xì)胞比例呈負(fù)相關(guān)性(P0.05);與血紅蛋白、白蛋白水平呈正相關(guān)性(P0.05)。結(jié)論糖尿病周圍神經(jīng)病變是導(dǎo)致糖尿病足潰瘍的重要危險因素。血糖控制差、感染、吸煙、胰島功能差、貧血、低蛋白血癥及下肢血供差均可能是糖尿病周圍神經(jīng)病變發(fā)生或發(fā)展的促進(jìn)因素。因此,預(yù)防和治療糖尿病足就應(yīng)該注重血糖控制、積極抗感染、改善或保護(hù)患者胰島功能、糾正貧血和低蛋白血癥,同時需注重對患者進(jìn)行糖尿病教育及足病知識教育。
[Abstract]:Objective to analyze the differences of electromyographic peroneal nerve conduction velocity between diabetic foot ulcer patients and type 2 diabetic patients without diabetic foot. Methods 54 patients with diabetic foot and 54 patients without diabetic foot were collected. Data on type 2 diabetic patients with diabetic foot, The clinical data of 108 patients with diabetic foot ulcers and type 2 diabetic patients without diabetic foot were analyzed retrospectively, and the difference of electromyography peroneal nerve conduction velocity and its influencing factors were studied. Results the diabetic foot group was compared with the control group. The lower extremity electromyography of peroneal nerve conduction velocity was slow, the difference was statistically significant (P 0.05). The two groups were educated, white blood cell count, neutrophil ratio, hemoglobin, albumin, There was a significant difference in ankle brachial index (ABI). There was a negative correlation between the conduction velocity of sensory nerve of peroneal nerve and glycosylated hemoglobin, white blood cell count, neutrophil ratio, and the level of fasting C-peptide, hemoglobin. There was a positive correlation between albumin and ABI. There was a negative correlation between peroneal nerve motor nerve conduction velocity and smoking time, glycosylated hemoglobin, neutrophilic granulocyte ratio. Conclusion Diabetic peripheral neuropathy is an important risk factor for diabetic foot ulcer. Hypoproteinemia and lower extremity blood supply may be the promotive factors for the occurrence or development of diabetic peripheral neuropathy. Therefore, the prevention and treatment of diabetic foot should pay attention to blood glucose control, actively anti-infection, improve or protect the pancreatic islet function of patients. To correct anemia and hypoproteinemia, attention should be paid to diabetes education and foot disease education.
【作者單位】： 安徽醫(yī)科大學(xué)第一附屬醫(yī)院內(nèi)分泌科;
【基金】：安徽省衛(wèi)生廳醫(yī)學(xué)科研重點(diǎn)項(xiàng)目(編號:2010A008)
【分類號】：R587.2

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本文編號：1497532