AIM:To develop a practical and reproducible rat model of hepatorenal syndrome for further study of the pathophysiology of human hepatorenal syndrome. METHODS:Sprague-Dawley rats were intravenously injected with D-galactosamine and lipopolysaccharide（LPS） via the tail vein to induce fulminant hepatic failure to develop a model of hepatorenal syndrome. Liver and kidney function tests and plasma cytokine levels were measured after D-galactosamine/LPS administration,and hepatic and renal pathology w... 

【文章來源】：World Journal of Gastroenterology. 2015,21(34)SCI

【文章頁數(shù)】：9 頁

【參考文獻(xiàn)】：
期刊論文
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