The phosphatase and tensin homolog（PTEN） and the zinc finger homeobox 3（ZFHX3）/AT-motif binding factor 1（ATBF1） genes have been established as tumor suppressor genes in prostate cancer by their frequent deletions and mutations in human prostate cancer and by the formation of mouse prostatic intraepithelial neoplasia（mPIN） or tumor by their deletions in mouse prostates.However,whether ZFHX3/ATBF1 deletion together with PTEN deletion facilitates prostatic tumorigenesis is unknown.In this study,we ... 

【文章來源】：Journal of Genetics and Genomics. 2015年07期

【文章頁數(shù)】：10 頁


本文編號：2913446