【摘要】：目的探討成人腎小球微小病變(minimal change disease,MCD)的臨床病理學(xué)特點。方法回顧性分析符合腎病綜合征(nephrotic syndrome,NS)、腎活檢病理診斷為MCD、年齡≥18周歲的162例成人患者的病理特征。結(jié)果對162例成人MCD腎組織病理改變進行統(tǒng)計發(fā)現(xiàn),腎小球球性硬化、腎間質(zhì)纖維化、腎間質(zhì)炎細胞浸潤、腎小管萎縮、腎血管病變的比率分別為32.7%、42.6%、55.6%、45.7%、37.0%,除腎間質(zhì)炎細胞浸潤,余病理改變的比率均隨著年齡的增長而增加。經(jīng)年齡糾正后,腎小球球性硬化的比率與患者年齡的關(guān)聯(lián)消失。結(jié)論成人MCD病理改變隨年齡增長,病變比例及嚴重程度均增高。
[Abstract]:Objective to investigate the clinicopathological features of adult glomerulonephritis (minimal change disease,MCD). Methods the pathological features of renal biopsy were retrospectively analyzed in 162 adult patients with nephrotic syndrome (nephrotic syndrome,NS) who were diagnosed by renal biopsy as MCD, 鈮，

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