烏魯木齊維吾爾族與漢族前列腺癌骨轉移患者差異性研究
[Abstract]:Objective to investigate the characteristics of bone metastasis in Uygur (Uygur) and Han patients with prostate cancer in Urumqi. Methods whole body radionuclide bone imaging was performed in 75 patients with prostate cancer of Uighur nationality and 82 patients with prostate cancer of Han nationality. Serum osteocalcin (BGP) levels were measured by radioimmunoassay and interleukin-6 (IL-6) was measured by chemiluminescence immunoassay. Free prostate specific antigen (F-PSA) and serum total prostate specific antigen (T-PSA) and their ratio (F / T). Results the positive rate of bone scintigraphy in Uygur nationality was 54.67% (75 cases), which was lower than that in the Han nationality 76.83% (82 cases). The levels of serum osteocalcin and IL-6 in Uygur nationality were significantly lower than those in the Han nationality (P0.05). There was no significant difference in serum F-PSA and T-PSA levels between the two nationalities (P0.05), but the ratio of F- / T was significantly higher in Uygur nationality than that in Han nationality (P0.05). Conclusion Bone metastasis is more likely to occur in Uygur and Han prostate cancer patients in Urumqi than in Han nationality, and the tumor metabolism index is active, the range of involvement is wide, and the prognosis is poor.
【作者單位】: 新疆維吾爾自治區(qū)人民醫(yī)院臨床檢驗中心;烏魯木齊市友誼醫(yī)院心內三科;
【基金】:新疆維吾爾自治區(qū)人民醫(yī)院院內項目(編號:20130116)
【分類號】:R737.25
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