【摘要】：目的了解慢性腎臟病(CKD)患者合并高血壓情況,并探討其影響因素。方法選取2013年3—7月,在新疆醫(yī)科大學第一附屬醫(yī)院腎病科接受住院治療的CKD患者228例。根據(jù)合并高血壓情況,將其分為非高血壓組(n=92)和高血壓組(n=136)。比較并分析兩組一般資料和各項實驗室檢測指標,探討CKD患者合并高血壓的影響因素。結(jié)果 (1)228例CKD患者的高血壓合并率為59.6%(136/228)。高血壓組和非高血壓組病因、合并癥中的糖尿病和心血管疾病、病情分期、平均年齡、收縮壓、舒張壓、尿酸及腎小球濾過率(GFR)比較,差異有統(tǒng)計學意義(P0.05);而性別、民族、文化程度、吸煙史、合并癥中的呼吸系統(tǒng)疾病、平均病程、24 h尿蛋白定量、三酰甘油、膽固醇及BMI比較,差異無統(tǒng)計學意義(P0.05)。(2)136例合并高血壓患者的高血壓治療率為96.3%(131/136),血壓控制率為45.6%(62/136)。不同病情分期患者的血壓控制率比較,差異無統(tǒng)計學意義(P0.05)。(3)Logistic回歸分析顯示,年齡、24 h尿蛋白定量及GFR對CKD患者合并高血壓的影響有統(tǒng)計學意義(P0.05)。結(jié)論 CKD患者的高血壓合并率較高,治療率較高,但控制率較差;年齡、24 h尿蛋白定量及GFR是其影響因素。
[Abstract]:Objective to investigate the prevalence of hypertension in patients with chronic kidney disease (CKD) and explore its influencing factors. Methods 228 CKD patients who were hospitalized in the Renal Department of the first affiliated Hospital of Xinjiang Medical University from March to July 2013 were selected. According to the condition of complicated hypertension, it was divided into two groups: non-hypertension group (n-92) and hypertension group (n-136). To compare and analyze the two groups of general data and various laboratory indicators to explore the influencing factors of hypertension in patients with CKD. Results (1) the incidence of hypertension in 228 patients with CKD was 59.6% (136 / 228). There were significant differences in etiology, diabetes and cardiovascular disease, stage of disease, mean age, systolic blood pressure, diastolic blood pressure, uric acid and glomerular filtration rate (GFR) between hypertension group and non-hypertension group (P0.05). Education, smoking history, respiratory diseases in complications, average duration of 24 h urinary protein quantification, triacylglycerol, cholesterol and BMI, There was no significant difference (P0.05). (2). The hypertension treatment rate was 96.3% (131 / 136), and the blood pressure control rate was 45.6% (62 / 136). There was no significant difference in blood pressure control rate between patients with different stages of the disease (P0.05). (3) Logistic regression analysis showed that the age of 24 hours urine protein quantitative and GFR on the CKD patients with hypertension had statistical significance (P0.05). Conclusion the incidence of hypertension in patients with CKD is higher, the rate of treatment is higher, but the control rate is poor, the quantitative analysis of urinary protein at 24 h and GFR are the influencing factors.
【作者單位】： 新疆醫(yī)科大學第一附屬醫(yī)院腎病科;
【基金】：新疆維吾爾自治區(qū)心血管病研究重點實驗室開放課題項目(XJDX0903-2011-06)
【分類號】：R692;R544.1

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