【摘要】：目的:通過探討精液液化異�；颊咝约に厮郊吧彻艿栏鞲綄傧袤w(附睪、精囊、前列腺等)功能狀態(tài),系統(tǒng)分析影響精液液化時(shí)間的相關(guān)因素,為精液液化異常的個(gè)體化診治提供臨床依據(jù)。方法:納入符合入組標(biāo)準(zhǔn)的育齡男性患者152例,根據(jù)精液液化時(shí)間將患者分為兩組:液化異常組(精液液化時(shí)間60 min組)和液化正常組(液化時(shí)間為≤60 min組)。測(cè)定精液常規(guī)參數(shù)、性激素5項(xiàng)及附屬腺體功能指標(biāo)精漿生化等。一是運(yùn)用T檢驗(yàn)比較兩組間生殖管道各附屬腺體功能狀態(tài)(p H值、中性α-糖苷酶、果糖、精漿鋅和檸檬酸)及性激素水平(FSH、LH、PRL、T和E2)是否存有顯著差異;二是運(yùn)用Logistic回歸分析檢測(cè)上述指標(biāo)與精液液化能力的相關(guān)性。結(jié)果:精液液化異常組(52例)與正常組(100例)相比,兩組間精液p H值(7.47±0.13 vs 7.32±0.18)、檸檬酸(51.12±12.95 vs 83.11±33.46)和FSH(4.40±1.03 vs 4.85±1.50)差異有統(tǒng)計(jì)學(xué)意義(P0.05),余差異無統(tǒng)計(jì)學(xué)意義。相關(guān)性回歸分析顯示,精液液化能力與精囊腺功能指標(biāo)果糖(OR=2.644)、前列腺功能指標(biāo)檸檬酸(OR=0.922)、血清T(OR=0.611)及E2(OR=1.029)水平存在相關(guān)性(P0.05),而與分析指標(biāo)中的其他因素?zé)o明顯關(guān)系。結(jié)論:精液的液化能力與兩腺體(前列腺/精囊腺)功能狀態(tài)及兩激素水平(T/E2)存在相關(guān)性,臨床診療精液液化異常患者時(shí),可根據(jù)具體致病因素給予區(qū)別化針對(duì)性治療。
[Abstract]:Objective: to investigate the levels of sex hormones and the functional status of the accessory glands (epididymis seminal vesicle prostate etc.) in patients with abnormal semen liquefaction and to systematically analyze the related factors affecting semen liquefaction time. To provide clinical basis for individual diagnosis and treatment of abnormal semen liquefaction. Methods: according to semen liquefaction time, 152 male patients of childbearing age were divided into two groups: abnormal liquefaction group (semen liquefaction time 60 min) and normal liquefaction group (liquefaction time 鈮，

本文編號(hào)：2138146