腎絞痛后輸尿管結(jié)石自排患者臨床特點研究
發(fā)布時間:2018-06-25 22:17
本文選題:輸尿管結(jié)石 + 腎絞痛 ; 參考:《石河子大學(xué)》2014年碩士論文
【摘要】:目的:輸尿管結(jié)石發(fā)病率和患病率逐年增加,其大多數(shù)可自行排出,但目前預(yù)測輸尿管結(jié)石排出的方法尚不完善。擬通過本前瞻性研究來發(fā)現(xiàn)輸尿管結(jié)石致腎絞痛患者的臨床特點,,并探討患者一般情況、實驗室檢查和影像學(xué)資料在預(yù)測輸尿管結(jié)石自行排出時的臨床應(yīng)用價值。 方法:收集2013年1月至8月因腎絞痛就診于我院泌尿外科門診的患者的臨床資料;颊叩呐R床資料包括一般情況,實驗室檢查及影像學(xué)資料。所有符合診斷標準和納入標準的患者均接受相同的藥物治療。一個月后復(fù)查泌尿系超聲或CT并根據(jù)患者結(jié)石的排出情況分為排石組和未排石組。使用單因素分析及多因素Logistic回歸分析來篩選預(yù)測因素。 結(jié)果:共入選275名患者,233名(64.36%)患者完成研究;颊叩哪挲g平均為41.77±14.86歲,男女比為3.1:1,其中138名(59.23%)患者4周內(nèi)結(jié)石自行排出。結(jié)石≤0.6cm的腎積水程度明顯小于結(jié)石0.6cm組,且差異具有統(tǒng)計學(xué)意義(P0.01)。輸尿管上段、中段、下段和膀胱壁內(nèi)段的結(jié)石平均大小為(0.78±0.16)cm、(0.76±0.15)cm、(0.69±0.14)cm和(0.74±0.19)cm,且差異具有統(tǒng)計學(xué)意義(P0.05),使用LSD-t檢驗法進行組間的多重比較,發(fā)現(xiàn)輸尿管上段結(jié)石和下段結(jié)石的差異仍具有統(tǒng)計學(xué)差異(P0.01)。疼痛程度為中度、重度和極重度的患者結(jié)石平均大小分別為(0.85±0.11)cm、(0.74±0.15)cm和(0.63±0.14)cm且差異具有統(tǒng)計學(xué)意義(P0.05),使用LSD-t檢驗法進行組間多重比較,發(fā)現(xiàn)三組間的差異仍有統(tǒng)計學(xué)意義(P0.05)。結(jié)石位于輸尿管上段、中段、下段及膀胱壁內(nèi)段的鏡下血尿發(fā)生率分別為62.50%、30.00%、66.20%和42.10%,且這種差異有統(tǒng)計學(xué)意義(P0.05)。單因素分析發(fā)現(xiàn)排石組和未排石組之間結(jié)石大小及位置、年齡、疼痛程度分級、血白細胞計數(shù)、中性粒細胞百分比、中性粒細胞計數(shù)、淋巴細胞百分比和CRP有統(tǒng)計學(xué)差異(P0.05),多因素Logistic回歸分析發(fā)現(xiàn)血白細胞計數(shù)、CRP、結(jié)石大小及位置是有統(tǒng)計學(xué)意義的因素(P0.05)。 結(jié)論:疼痛程度分級越高,輸尿管結(jié)石越小。而輸尿管結(jié)石越大,腎盂積水程度越重。和結(jié)石大小及位置一樣,血白細胞計數(shù)和CRP可能是預(yù)測輸尿管結(jié)石自行排出的獨立因素。
[Abstract]:Objective: the incidence and prevalence of ureteral calculi increase year by year, most of them can be discharged by themselves, but the method of predicting ureteral calculi is not perfect. The purpose of this prospective study was to find out the clinical features of renal colic caused by ureteral calculi, and to explore the clinical application value of general condition, laboratory examination and imaging data in predicting the spontaneous discharge of ureteral calculi. Methods: from January to August, 2013, the clinical data of patients with renal colic in Urology outpatient department of our hospital were collected. The clinical data of the patients include general information, laboratory examination and imaging data. All patients who met the diagnostic criteria and the inclusion criteria received the same medication. One month later, the urological ultrasound or CT was reexamined and divided into two groups according to the excretion of stone. Single factor analysis and multivariate logistic regression analysis were used to screen predictive factors. Results: a total of 275 patients (64.36%) completed the study. The average age of the patients was 41.77 鹵14.86 years old, and the ratio of male to female was 3.1: 1. 138 patients (59.23%) had stones excreted by themselves within 4 weeks. The degree of hydronephrosis in patients with stones 鈮
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