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膀胱三維幾何及特征映射模型研究

發(fā)布時(shí)間:2018-06-25 22:18

  本文選題:膀胱 + 幾何模型。 參考:《西北大學(xué)》2014年碩士論文


【摘要】:膀胱腫瘤是男性第四大易發(fā)腫瘤,具有致死率、復(fù)發(fā)率高等特點(diǎn),早診斷早治療是防治關(guān)鍵。虛擬內(nèi)窺鏡技術(shù)是一種無(wú)創(chuàng)、無(wú)痛、前景可觀(guān)的管腔內(nèi)部腫瘤檢查方法,近年來(lái)在體檢中被廣泛采用。基于虛擬內(nèi)窺鏡的膀胱腫瘤計(jì)算機(jī)輔助檢測(cè)技術(shù),主要包括膀胱器官三維重建,表面腫瘤形態(tài)、紋理描述及建模等,可為醫(yī)生提供更加直觀(guān)的檢測(cè)和診斷參考。 本文研究了基于曲面參數(shù)膀胱器官的幾何和紋理建模方法,具體內(nèi)容有: (1)提出了一種半自動(dòng)的膀胱壁分割算法——基于層間擴(kuò)散的Snake算法,該方法可以有效的將膀胱壁從MRI數(shù)據(jù)中分割出來(lái)。 (2)提出了一種面向點(diǎn)云的表面重建算法,利用自由變形技術(shù)將初始的參數(shù)模型迭代擬合至膀胱點(diǎn)云輪廓,生成膀胱的參數(shù)變形模型,即膀胱幾何模型。由于膀胱模型是參數(shù)變形模型,所以很容易對(duì)其渲染可視化顯示、量化比較及快速檢索等。 (3)提出了基于參數(shù)變形模型的特征投影技術(shù),將點(diǎn)云的表面特征(厚度特征、紋理特征等)映射至參數(shù)模型表面,形成二維特征映射模型有利于計(jì)算機(jī)輔助腫瘤的快速檢測(cè)。 (4)提出了膀胱的歸一化模型。將任意膀胱器官映射至標(biāo)準(zhǔn)化圓球球形模型上,為膀胱提供了統(tǒng)一的表達(dá)和量化比較方法。 理論推導(dǎo)和實(shí)驗(yàn)均表明,本文提出的模型可以描述了膀胱的整體形狀,更有表面局部細(xì)節(jié)特征的描述能力,為醫(yī)生提供了可度量和更加深入的可視化方法,也為后期的計(jì)算機(jī)輔助檢測(cè)提供了更好的基礎(chǔ)。
[Abstract]:Bladder tumor is the fourth most prone tumor in men, with the characteristics of mortality and high recurrence rate. Early diagnosis and treatment is the key to prevention and treatment. Virtual endoscopy is a noninvasive painless and promising method for the examination of intraluminal neoplasms which has been widely used in medical examination in recent years. The computer-aided detection technology of bladder tumor based on virtual endoscope, which mainly includes three-dimensional reconstruction of bladder organ, shape of surface tumor, texture description and modeling, can provide more intuitionistic detection and diagnosis reference for doctors. In this paper, geometric and texture modeling methods of bladder organs based on curved surface parameters are studied. The main contents are as follows: (1) A semi-automatic bladder wall segmentation algorithm, Snake algorithm based on interlayer diffusion, is proposed. This method can effectively segment the bladder wall from MRI data. (2) A point cloud oriented surface reconstruction algorithm is proposed. The initial parameter model is iteratively fitted to the point cloud profile by free deformation technique. The parametric deformation model of the bladder is generated, that is, the geometric model of the bladder. Because bladder model is parametric deformation model, it is easy to render visual display, quantitative comparison and fast retrieval. (3) feature projection technology based on parameter deformation model is proposed. The surface features (thickness feature, texture feature, etc.) of the point cloud are mapped to the surface of the parameter model to form a two-dimensional feature mapping model. (4) A normalized model of bladder is proposed. By mapping any bladder organ to a standardized spherical sphere model, a unified expression and quantitative comparison method is provided for the bladder. Both theoretical and experimental results show that the proposed model can describe the global shape of the bladder, have the ability to describe the local details of the surface, and provide a measurable and more in-depth visualization method for doctors. It also provides a better basis for later computer aided detection.
【學(xué)位授予單位】:西北大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2014
【分類(lèi)號(hào)】:TP391.41;R737.14

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