發(fā)布時(shí)間：2018-06-03 02:24

  本文選題：前列腺增生癥 + 高血壓�。� 參考：《廣東醫(yī)學(xué)》2017年08期

【摘要】：目的探討心腦血管疾病危險(xiǎn)因素高血壓、糖尿病、肥胖、血脂異常與良性前列腺增生癥(BPH)的關(guān)系。方法選取205例BPH患者的臨床資料,然后分別按照是否合并高血壓、糖尿病、肥胖、血脂異常分為BPH非高血壓組(A1組,n=115)和BPH合并高血壓組(A2組,n=90)、BPH非高血糖組(B1組,n=169)和BPH合并高血糖組(B2組,n=36)、BPH非肥胖組(C1組,n=142)和BPH合并肥胖組(C2組,n=63)、BPH非血脂異常組(D1組,n=151)和BPH合并血脂異常組(D2組,n=54),再分別進(jìn)行兩組間回顧性對(duì)比分析;最后進(jìn)一步分析前列腺體積(PV)分別與收縮壓(SBP)、舒張壓(DBP)、空腹血糖(FBG)、糖化血紅蛋白(HbA_(1C))、體質(zhì)指數(shù)(BMI)、總膽固醇(TC)、三酰甘油(TG)、高密度脂蛋白膽固醇(HDL-C)、低密度脂蛋白膽固醇(LDL-C)和血清前列腺特異性抗原(PSA)之間的相關(guān)性。結(jié)果 BPH分別合并高血壓、糖尿病、肥胖患者與單純性BPH患者相比,PV增大[(66.21±20.78)mL vs(56.79±29.31)mL、(68.98±27.67)mL vs(59.20±21.02)mL、(67.01±18.98)mL vs(58.45±23.64)mL],差異有統(tǒng)計(jì)學(xué)意義(P0.05);并且高血壓分級(jí)與PV呈正相關(guān)(rs=0.321,P0.05);同樣SBP、DBP、FBG、BMI、血清總PSA(t-PSA)和血清游離PSA(f-PSA)與PV呈正相關(guān)(r=0.229,P0.05;r=0.188,P0.05;r=0.180,P0.05;r=0.311,P0.05;r=0.161,P0.05;r=0.161,P0.05)。結(jié)論高血壓、糖尿病、肥胖可能分別是促發(fā)BPH的危險(xiǎn)因素,控制血壓、血糖、體重可作為預(yù)防前列腺增生的手段之一。
[Abstract]:Objective to investigate the relationship between hypertension, diabetes, obesity, dyslipidemia and benign prostatic hyperplasia (BPH). Methods the clinical data of 205 patients with BPH were selected, and then according to whether the patients were complicated with hypertension, diabetes, obesity, Dyslipidemia was divided into two groups: BPH non-hypertension group (A-1), BPH with hypertension group A _ 2 (group A _ 2) and BPH with hyperglycemia group B _ 1 (group B _ 1) and BPH with hyperglycemia group B _ 2 (group B _ 2) and BPH group with obesity group C _ 2 group without hyperlipidemia group C _ 2 group with no hyperlipidemia group D _ 1). BPH combined with dyslipidemia group (D 2 group) and D 2 group (P < 0.05) were compared and analyzed retrospectively between the two groups. Finally, we further analyze the relationship between SBP, DBP, FBGG, HbA1C, BMI, TC, TG, HDL-C, LDL-C. The correlation between LDL-C and serum prostate specific antigen (PSA). Results BPH was associated with hypertension and diabetes respectively. 鑲ヨ儢鎮(zhèn)ｈ，

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