本文選題：256層螺旋CT + 動脈性勃起功能障礙�。� 參考：《昆明醫(yī)科大學(xué)》2017年碩士論文

【摘要】：[目的]研究256層螺旋CT灌流造影對動脈性勃起功能障礙的診斷價(jià)值。[方法]對20例無勃起功能障礙成年男性(對照組)及72例診斷為動脈性勃起功能障礙患者(研究組)分別行下腹部256層螺旋CT灌注掃描檢查,通過256層螺旋CT灌注成像專用軟件重建陰莖血管三維影像,采集陰莖海綿體中段處雙側(cè)海綿體組織(感興趣區(qū)5mm2)內(nèi)動脈的相關(guān)灌注參數(shù),如TTP(造影劑密度達(dá)到高峰的時(shí)間)、BF(每分鐘流經(jīng)100g海綿體組織的血流量單位:ml/100g.min)、BV (每100g海綿體組織的血管床容積單位:ml/100g)等數(shù)據(jù),并進(jìn)行影像學(xué)和統(tǒng)計(jì)學(xué)分析。[結(jié)果]對照組雙側(cè)海綿體動脈的TTP、BF、BV對比無明顯差異(P0.05),CT片顯示本組雙側(cè)海綿體動脈連續(xù)顯影較好,重建陰莖血管三維影像可以發(fā)現(xiàn)雙側(cè)陰莖海綿體動脈呈連續(xù)性影像。72例研究組中有63例患者CT片顯示單側(cè)陰莖海綿體動脈未顯影或顯影不連續(xù)而另一側(cè)顯影較好,9例患者CT片顯示雙側(cè)陰莖海綿體動脈未顯影。63例患者中發(fā)生在左側(cè)未顯影或顯影不連續(xù)的占36例,發(fā)生在右側(cè)未顯影或顯影不連續(xù)的占27例,利用256層螺旋CT的專用軟件重建這63例患者陰莖血管三維影像并進(jìn)行陰莖海綿體灌注血流動力學(xué)研究,發(fā)現(xiàn)該組的雙側(cè)海綿體動脈灌注參數(shù)TTP值、BF值、BV值之間對比有明顯差異(P0.05),其中狹窄一側(cè)海綿體動脈灌注參數(shù)TTP值、BF值、BV值均較對側(cè)低,且與對照組對比有明顯統(tǒng)計(jì)學(xué)差異(P0.05);剩下的9例患者其CT灌注掃描雙側(cè)陰莖海綿體動脈未見顯影,重建這9例陰莖血管三維影像發(fā)現(xiàn)該組的雙側(cè)陰莖海綿體動脈均不能顯示。[結(jié)論]利用256層螺旋CT灌注重建陰莖血管三維成像,獲取相關(guān)灌注參數(shù)能夠很好地研究陰莖血流動力學(xué)的變化,同時(shí)也能較好地顯示陰莖血管和海綿體的病變部位,與其他檢查手段相比,具有創(chuàng)傷小,費(fèi)用低的優(yōu)點(diǎn),開創(chuàng)了一種對于動脈性勃起功能障礙診斷的新方法。
[Abstract]:[objective] to study the diagnostic value of 256-slice spiral CT perfusion angiography in arterial erectile dysfunction. [methods] Twenty adult men without erectile dysfunction (control group) and 72 patients diagnosed as arterial erectile dysfunction (study group) were examined with 256-slice spiral CT perfusion scan of lower abdomen, respectively. Three-dimensional images of penile vessels were reconstructed by 256-slice spiral CT perfusion imaging software. The perfusion parameters of bilateral cavernous tissue (5mm ~ 2 mm) were collected at the middle segment of the corpus cavernosum. Data such as TTP (volume of blood flow through 100g cavernous tissue per minute: ml / 100g / min) (volume of vascular bed volume per 100g cavernous tissue: 1 / ml / 100g) and imaging and statistical analysis were performed. [results] in the control group, there was no significant difference in TTPTV-BFFV between the bilateral cavernous arteries and the continuous development of bilateral cavernous arteries was demonstrated by P0.05 CT film. Three-dimensional reconstruction of penis vessels can be found that bilateral cavernous artery in the study group of 72 cases in the study group of 63 patients with CT images of unilateral cavernous artery did not develop or develop discontinuous, the other side of the development is better. Ct findings of bilateral cavernous artery in 9 cases. Of 63 cases, 36 cases occurred in left side without or discontinuous development. There were 27 cases without or discontinuous development on the right side. Three-dimensional images of penile vessels were reconstructed by 256-slice spiral CT software, and hemodynamics of penile cavernous perfusion was studied. It was found that there were significant differences in the TTP value and BF value and BV value of bilateral cavernous artery perfusion parameters in this group (P < 0.05), in which the TTP value and BF value and BV value of cavernous artery perfusion parameter in the narrow side were lower than those in the contralateral side. Compared with the control group, there was a significant difference between the two groups (P 0.05), the remaining 9 patients had no CT perfusion scan of bilateral cavernous artery, and the reconstruction of 9 cases showed that the bilateral cavernous artery could not be displayed. [conclusion] using 256-slice spiral CT perfusion to reconstruct the penile vessels and obtain the relevant perfusion parameters can well study the changes of penile hemodynamics, and at the same time, it can also better display the pathological location of penile vessels and cavernous bodies. Compared with other examination methods, it has the advantages of less trauma and lower cost, thus creating a new method for the diagnosis of arterial erectile dysfunction.
【學(xué)位授予單位】：昆明醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R698.1

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