本文選題：腎盂及輸尿管取石術(shù) + 切口感染��； 參考：《中華醫(yī)院感染學(xué)雜志》2017年23期

【摘要】：目的調(diào)查分析121例腎盂及輸尿管取石術(shù)患者術(shù)后切口感染的病原菌分布及多種耐藥菌耐藥性情況,以期為預(yù)防感染的發(fā)生及感染的后期治療提供幫助。方法回顧性分析2013年7月-2015年7月醫(yī)院收治的腎盂及輸尿管取石術(shù)患者489例,對(duì)其中121例術(shù)后切口感染患者進(jìn)行調(diào)查分析,取其標(biāo)本做細(xì)菌培養(yǎng)和藥敏試驗(yàn),分析術(shù)后感染多種耐藥菌分布及其耐藥性情況。結(jié)果 489例腎盂及輸尿管取石術(shù)患者中121例發(fā)生術(shù)后切口感染,感染率為24.74%;傳統(tǒng)開放性切開術(shù)后切口感染率最高,感染率為40.32%;121例送檢標(biāo)本分離出病原菌128株,以革蘭陰性菌為主,共94株占73.44%;128株病原菌中多藥耐藥菌72株,占56.25%;大腸埃希菌對(duì)亞胺培南和磺胺甲VA唑/甲氧芐啶耐藥率較低,克雷伯桿菌對(duì)亞胺培南和左氧氟沙星耐藥率較低。結(jié)論為減少腎盂及輸尿管取石術(shù)后切口感染率,需積極采取有效的措施,根據(jù)藥敏實(shí)驗(yàn)結(jié)果,合理選擇抗菌藥物,有效控制感染。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria and drug resistance of multi-drug resistant bacteria in 121 cases of postoperative incision infection of renal pelvis and ureterolithotomy so as to provide help for prevention of infection and late treatment of infection. Methods from July 2013 to July 2015, 489 cases of renal pelvis and ureterolithotomy were retrospectively analyzed. 121 cases of postoperative incision infection were investigated and analyzed. The specimens were collected for bacterial culture and drug sensitivity test. To analyze the distribution and drug resistance of multidrug resistant bacteria infected after operation. Results among 489 cases of renal pelvis and ureterolithotomy, 121 cases had postoperative incision infection, the infection rate was 24.74%, the infection rate of incision after traditional open incision was the highest, the infection rate was 40.3232 + 121 samples, 128 strains of pathogenic bacteria were isolated. Gram-negative bacteria were the main pathogens, and the resistance rate of Escherichia coli to imipenem and sulfamethoxazole / trimethoprim was low, among which 72 were multidrug resistant strains (56.25%). The resistance of Klebsiella to imipenem and levofloxacin was low. Conclusion in order to reduce the infection rate of incision after renal pelvis and ureterolithotomy, effective measures should be taken. According to the results of drug sensitivity test, antibiotics should be reasonably selected to control infection effectively.
【作者單位】： 福建醫(yī)科大學(xué)附屬第二醫(yī)院泌尿外科;
【基金】：福建省自然科學(xué)基金資助項(xiàng)目(2012J01372)
【分類號(hào)】：R446.5;R699

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