本文選題：前列腺癌 + 良性前列腺增生��； 參考：《中國(guó)老年學(xué)雜志》2017年02期

【摘要】：目的探討良性前列腺增生癥(BPH)患者術(shù)后再發(fā)前列腺癌的臨床特點(diǎn)。方法分析24例BPH術(shù)后再發(fā)前列腺癌患者資料,根據(jù)主訴分為肉眼血尿組和排尿困難組,又根據(jù)BPH手術(shù)方式分為前列腺開(kāi)放手術(shù)組與經(jīng)尿道前列腺電切術(shù)(TURP)術(shù)組,觀察兩組間發(fā)病年齡、與BPH手術(shù)間隔時(shí)間、前列腺體積、血前列腺特異性抗原(PSA)水平及Gleason評(píng)分的差別,分析低分化腺癌、Ⅳ期和硬結(jié)發(fā)生率。結(jié)果前列腺開(kāi)放手術(shù)與TURP術(shù)后兩組發(fā)病年齡、術(shù)后間隔時(shí)間、前列腺體積、血PSA、臨床分期(F=0.727,P=0.403)無(wú)顯著性差異。血尿組與排尿困難兩組發(fā)病年齡、術(shù)后間隔時(shí)間、血PSA、Gleason評(píng)分、低分化腺癌發(fā)病率無(wú)顯著性差異,血尿組前列腺體積較排尿困難組大(F=5.923,P=0.024)。血尿組硬結(jié)發(fā)生率明顯高于排尿困難組(P0.05),臨床分期晚于排尿困難組(P0.05)。結(jié)論 BPH手術(shù)治療(包括TURP)后再發(fā)的前列腺癌其臨床表現(xiàn)和治療原則基本同原發(fā)性前列腺癌。手術(shù)僅切除增生腺體,存留壓迫、萎縮變形之外周帶可能是術(shù)后前列腺癌再發(fā)的主要起源,再發(fā)癌可能與前列腺干細(xì)胞增殖、演變有關(guān)。BPH術(shù)后定期隨訪觀察非常重要,可盡早發(fā)現(xiàn)癌變,做到早診斷早治療。
[Abstract]:Objective to investigate the clinical features of recurrent prostate cancer in patients with benign prostatic hyperplasia (BPH).Methods Twenty-four patients with recurrent prostate cancer after BPH were divided into naked hematuria group and dysuria group according to the main complaint. The patients were divided into open prostate operation group and transurethral resection of prostate group according to BPH operation.The age of onset, the interval between operation and BPH, the volume of prostate, the level of serum prostate specific antigen (PSA) and the Gleason score were observed, and the incidence of poorly differentiated adenocarcinoma, stage 鈪，

本文編號(hào)：1756413