本文選題：血液凈化方法　切入點(diǎn)：膿毒癥急性腎損傷　出處：《中國(guó)老年學(xué)雜志》2017年24期

【摘要】：目的探討不同血液凈化方法對(duì)膿毒癥急性腎損傷(SAKI)患者血流動(dòng)力學(xué)及預(yù)后的影響。方法選擇SAKI患者136例,根據(jù)血液凈化方式的不同分為觀察組和對(duì)照組各68例,兩組均給予常規(guī)針對(duì)性治療,并給予血液凈化治療,觀察組選擇連續(xù)性腎臟替代療法(CRRT),對(duì)照組選擇間歇性血液透析(IHD),監(jiān)測(cè)并對(duì)比兩組預(yù)后指標(biāo)、血流動(dòng)力學(xué)指標(biāo)[心率(HR),平均動(dòng)脈壓(MAP),血氧飽和度(Sa O2)]、實(shí)驗(yàn)室指標(biāo)(血肌酐和白蛋白),并對(duì)比兩組不同時(shí)期急性生理學(xué)及慢性健康狀況評(píng)分(APACHE)Ⅱ變化值及少尿天數(shù)。結(jié)果觀察組腎功能恢復(fù)率較對(duì)照組明顯升高(P0.05)。治療后兩組HR明顯降低,且觀察組明顯低于對(duì)照組,MAP和Sa O2水平均明顯升高(均P0.05)。治療后兩組APACHEⅡ評(píng)分和血肌酐水平明顯降低,且觀察組明顯低于對(duì)照組,白蛋白水平明顯高于對(duì)照組(均P0.05)。觀察組Ⅰ期患者APACHEⅡ評(píng)分變化值明顯大于對(duì)照組,而少尿天數(shù)明顯少于對(duì)照組(均P0.05)。結(jié)論應(yīng)用CRRT與IHD方式均可有效治療SAKI患者,能夠改善患者血流動(dòng)力學(xué)及預(yù)后,但CRRT的腎功能恢復(fù)率更高,對(duì)Ⅰ期SAKI患者的預(yù)后更好。
[Abstract]:Objective to investigate the effect of different blood purification methods on hemodynamics and prognosis of patients with septic acute renal injury.Methods one hundred and thirty-six patients with SAKI were divided into observation group (n = 68) and control group (n = 68).Continuous renal replacement therapy (CRRTT) was used in the observation group and intermittent hemodialysis (IHD) was used in the control group to monitor and compare the prognostic indexes of the two groups.Results the recovery rate of renal function in the observation group was significantly higher than that in the control group (P 0.05).After treatment, the HR of the two groups decreased significantly, and the levels of map and SaO2 in the observation group were significantly lower than those in the control group (P 0.05).After treatment, the APACHE 鈪，

本文編號(hào)：1700186