本文選題：前列腺癌　切入點：超聲造影　出處：《新疆醫(yī)科大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:探討前列腺超聲造影(Contrast-enhance ultrasound CEUS)、磁共振(Magnetic resonance imaging MRI)增強及其聯(lián)合成像在不同前列腺特異性抗原(Prostate sPecific antigen PSA)區(qū)間前列腺癌(Prostatic cancer PCa)診斷中的臨床應(yīng)用價值。方法:回顧性分析132例疑似前列腺癌患者,均行CEUS、MRI增強檢查,并進一步經(jīng)直腸前列腺穿刺活檢術(shù)證實,結(jié)合病理結(jié)果比較分析兩種診斷方法及其聯(lián)合成像在前列腺癌診斷中臨床應(yīng)用價值。結(jié)果:CEUS、MRI增強及二者聯(lián)合應(yīng)用對前列腺癌診斷的靈敏度分別為75.43%、80.70%、92.98%,特異度分別為77.33%、86.67%、73.33%,二者聯(lián)合診斷的靈敏度高于CEUS、MRI增強單獨一種技術(shù),差異均具有統(tǒng)計學(xué)意義(P0.05),MRI增強診斷的特異度高于聯(lián)合診斷,差異有統(tǒng)計學(xué)意義(P0.05)�；颊咴�4PSA≤10ng/ml范圍內(nèi),CEUS、MRI增強及二者聯(lián)合應(yīng)用特異度分別為82.00%、96.00%、80.00%,MRI增強診斷特異度高于CEUS及二者聯(lián)合應(yīng)用,差異均有統(tǒng)計學(xué)意義(P0.05)。在10PSA≤20ng/ml范圍內(nèi),CEUS、MRI增強及二者聯(lián)合應(yīng)用對前列腺癌診斷的靈敏度分別為42.86%、52.38%、80.95%,特異度分別為73.68%、68.42%、63.16%,二者聯(lián)合應(yīng)用診斷的靈敏度高于CEUS、MRI增強單獨一種技術(shù),差異均具有統(tǒng)計學(xué)意義(P0.05)。在PSA20ng/ml中,三種方法均診斷正確。結(jié)論:CEUS與MRI增強對前列腺癌診斷各有優(yōu)勢,二者聯(lián)合診斷可以提高靈敏度,優(yōu)于單獨一種診斷方法。同時MRI增強對前列腺癌診斷的特異度優(yōu)于聯(lián)合診斷方法。在4PSA≤10ng/ml區(qū)間,MRI增強具有較高的診斷特異性,有診斷優(yōu)勢;10PSA≤20ng/ml中,CEUS和MRI增強聯(lián)合應(yīng)用具有較高的靈敏度,具有診斷優(yōu)勢;在PSA20ng/ml中CEUS檢查簡便,可提高前列腺穿刺活檢定位準確性,具有診斷優(yōu)勢。
[Abstract]:Objective: to evaluate the clinical value of contrast-enhanced ultrasound ultrasound enhanced Mr magnetic resonance imaging MRI and its combined imaging in the diagnosis of prostatic cancer PCA with different prostate sPecific antigen PSAs. Methods: a retrospective review was made. Sex analysis of 132 suspected prostate cancer patients, All patients were examined by CEUSUS MRI and confirmed by transrectal prostatic biopsy. The clinical value of two diagnostic methods and their combined imaging in the diagnosis of prostate cancer was compared with pathological results. Results the sensitivity of enhanced MRI and combined use of the two methods in the diagnosis of prostate cancer was 75.4343 and 80.70, respectively. The specificity of the two methods was 75.4343 and 80.70, respectively. The specificity of the two methods was 75.4343 and 80.70, respectively. The sensitivity of the combined diagnosis of the two is higher than that of the CEUST MRI enhanced by a single technique, 77.33 / 86.67 / 73.33 / 77.33 / 77.33 / 86.67 / 73.33, respectively. The difference was statistically significant. The specificity of enhanced MRI was higher than that of combined diagnosis. In the range of 4PSA 鈮，

本文編號：1642462