本文選題：腎細(xì)胞腫瘤　切入點(diǎn)：轉(zhuǎn)移性　出處：《臨床與實(shí)驗(yàn)病理學(xué)雜志》2017年03期 　論文類型：期刊論文

【摘要】：目的 探討管狀囊性腎細(xì)胞癌(tubulocystic renal cell carcinoma,TRCC)的臨床病理特征、診斷與鑒別診斷。方法對(duì)1例60歲男性患者額部轉(zhuǎn)移性TRCC行HE及免疫組化En Vison兩步法染色,光鏡下觀察組織形態(tài)學(xué)特征,并復(fù)習(xí)相關(guān)文獻(xiàn)。結(jié)果 鏡下可見(jiàn)腫瘤由纖細(xì)的纖維性間質(zhì)分隔的大小不等的囊狀和小管結(jié)構(gòu)組成,囊腔內(nèi)含嗜伊紅蛋白,囊腔內(nèi)襯覆扁平或柱狀上皮細(xì)胞,部分呈“鞋釘樣”突向腔內(nèi)。細(xì)胞核圓形或卵圓形,空泡狀,可見(jiàn)核仁,Fuhrman核3級(jí),核分裂象不易見(jiàn),胞質(zhì)豐富,嗜酸性。免疫表型:腫瘤細(xì)胞vimentin、P504s、CK19、CKpan和EMA均呈彌漫強(qiáng)陽(yáng)性,CD10和CK7均呈陰性,Ki-67增殖指數(shù)5%。結(jié)論 TRCC十分罕見(jiàn),好發(fā)于成年男性,大部分患者預(yù)后良好,復(fù)發(fā)和轉(zhuǎn)移者罕見(jiàn),轉(zhuǎn)移性病灶依賴于病理學(xué)診斷,并為原發(fā)灶的查找提供重要線索和依據(jù)。
[Abstract]:Objective to investigate the clinicopathological features, diagnosis and differential diagnosis of tubular cystic renal cell carcinoma (renal cell carcinomata cell). Results the tumor was composed of fine fibrous mesenchymal mesenchymal mesenchymal cysts and tubules with eosinophils in the cysts. The cystic cavity was lined with flat or columnar epithelial cells, some of which were "shoe-like" protruding into the cavity. The nucleus was round or oval, vacuolated, and Fuhrman nuclear grade 3 could be seen. The mitotic appearance was not easy to see and the cytoplasm was abundant. Eosinophilic and immunophenotype: tumor cell line P504sCCK19CKpan and EMA were both strongly diffusely positive, CD10 and CK7 were both negative. Conclusion TRCC is very rare in adult males. The prognosis of most of the patients is good, and recurrence and metastasis are rare. Metastatic lesions depend on pathological diagnosis and provide important clues and evidences for finding primary lesions.
【作者單位】： 福建中醫(yī)藥大學(xué)附屬人民醫(yī)院病理科;南京軍區(qū)福州總醫(yī)院病理科;
【分類號(hào)】：R737.11

【相似文獻(xiàn)】

相關(guān)會(huì)議論文 前3條

1 管維;朱旋;楊為民;陳志強(qiáng);葉章群;;房囊性腎細(xì)胞癌2例報(bào)道及文獻(xiàn)復(fù)習(xí)[A];第十五屆全國(guó)泌尿外科學(xué)術(shù)會(huì)議論文集[C];2008年

2 劉剛;;囊性腎細(xì)胞癌12例診治體會(huì)[A];第十五屆全國(guó)泌尿外科學(xué)術(shù)會(huì)議論文集[C];2008年

3 劉鋒;章越龍;張大宏;;經(jīng)腹腔途徑腹腔鏡腎癌根治術(shù)112例經(jīng)驗(yàn)總結(jié)[A];2011年浙江省微創(chuàng)外科學(xué)術(shù)會(huì)議論文匯編[C];2011年

相關(guān)碩士學(xué)位論文 前3條

1 翁明高;囊性腎細(xì)胞癌（附12例報(bào)告）[D];福建醫(yī)科大學(xué);2002年

2 全許譽(yù);囊性腎細(xì)胞癌的診斷與治療（附18例報(bào)告）[D];廣西醫(yī)科大學(xué);2015年

3 高回青;超聲與CT診斷囊性腎細(xì)胞癌的比較影像學(xué)研究[D];蘇州大學(xué);2011年

，

本文編號(hào)：1630841