本文選題：穿刺介入手術(shù)　切入點(diǎn)：變形模型　出處：《天津大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：本文研究了穿刺治療手術(shù)中影響放射性粒子植入精度的兩大主要因素—柔性針變形和軟組織變形。并結(jié)合具有相同人體解剖結(jié)構(gòu)的盆腔器官群模型,深入探討了前列腺穿刺過程中柔性針與軟組織力學(xué)交互機(jī)理和靶點(diǎn)誤差變化規(guī)律。研究結(jié)果有助于正確認(rèn)識(shí)穿刺粒子植入手術(shù)過程中誤差的產(chǎn)生機(jī)理與補(bǔ)償方法,可以應(yīng)用于術(shù)前軌跡規(guī)劃、劑量規(guī)劃、手術(shù)模擬訓(xùn)練等領(lǐng)域。主要內(nèi)容如下所述:首先,根據(jù)針刺力實(shí)驗(yàn),建立了柔性針變形模型。重點(diǎn)研究了柔性針與軟組織的交互作用,并對(duì)柔性針和軟組織相關(guān)參數(shù)進(jìn)行參數(shù)化分析。通過針穿刺實(shí)驗(yàn)與模型敏感度分析,分析并驗(yàn)證了針變形模型在不同參量影響下的有效性。其次,以柔性針變形為輸入量,采用有限元方法,研究了穿刺過程中的軟組織變形。根據(jù)柔性針與軟組織的力學(xué)交互,得到了目標(biāo)點(diǎn)位置的偏移量。結(jié)合解剖學(xué)知識(shí)和三維重建技術(shù)將變形模擬擴(kuò)展到三維器官群,計(jì)算出總體穿刺誤差。最終通過實(shí)驗(yàn)進(jìn)行誤差補(bǔ)償最后,根據(jù)重建器官的空間位置及外形尺寸參數(shù),制作人造器官群模具,參考各器官與組織在人體中的實(shí)際約束關(guān)系,對(duì)具有自主知識(shí)產(chǎn)權(quán)的水凝膠軟組織器官群進(jìn)行裝配。分別搭建了力學(xué)和變形實(shí)驗(yàn)平臺(tái),進(jìn)行器官群針刺力學(xué)實(shí)驗(yàn)與誤差驗(yàn)證實(shí)驗(yàn)。
[Abstract]:In this paper, two main factors that affect the precision of radioactive particle implantation in puncture treatment are studied, which are flexible needle deformation and soft tissue deformation, and combined with pelvic organ swarm model with the same anatomical structure of human body. The interaction mechanism of flexible needle and soft tissue mechanics and the variation of target error in the process of prostate puncture are discussed in depth. The results are helpful to correctly understand the mechanism and compensation method of errors in the process of puncture particle implantation. It can be used in the fields of preoperative trajectory planning, dose planning, surgical simulation training and so on. The main contents are as follows: firstly, according to the acupuncture force experiment, a flexible needle deformation model is established, and the interaction between flexible needle and soft tissue is mainly studied. Through the needle puncture experiment and the sensitivity analysis of the model, the validity of the needle deformation model under the influence of different parameters is analyzed and verified. Secondly, the flexible needle deformation is taken as the input quantity. The soft tissue deformation during puncture was studied by finite element method. According to the mechanical interaction between flexible needle and soft tissue, The displacement of the target point is obtained. Combined with anatomical knowledge and 3D reconstruction technique, the deformation simulation is extended to the three-dimensional organ group, and the total puncture error is calculated. Finally, the error compensation is carried out through experiments. According to the parameters of space position and shape size of reconstructed organs, the mould of artificial organ group is made, and the actual constraint relation between organs and tissues in human body is referred to. The hydrogel soft tissue organ group with independent intellectual property rights was assembled, and the mechanical and deformation experiment platforms were set up, and the acupuncture mechanics experiment and error verification experiment of organ group were carried out.
【學(xué)位授予單位】：天津大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R737.25

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 李忠勇;高惠波;金小海;陳大明;;近距離治療腫瘤的放射性粒子研究進(jìn)展[J];同位素;2011年02期

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本文編號(hào)：1606855