本文選題：腎積水　切入點(diǎn)：腎小球?yàn)V過率　出處：《山東醫(yī)藥》2016年37期 　論文類型：期刊論文

【摘要】：目的探討Gates法計(jì)算的腎小球?yàn)V過率(GFR)對(duì)單側(cè)腎積水患者腎小球?yàn)V過功能評(píng)估的價(jià)值。方法選擇經(jīng)B超檢查確診為單側(cè)腎積水的患者176例(輕度積水組21例、中度積水組33例、重度積水組122例),同期選取泌尿系統(tǒng)及GFR均正常的腎移植供體捐獻(xiàn)者22例(正常對(duì)照組)。兩組均接受99mTc-DTPA腎動(dòng)態(tài)顯像檢查,用Gates法計(jì)算患腎、健腎、雙腎GFR值,根據(jù)單腎GFR將患者腎功能劃分為腎功能正常、輕度下降、中度下降、重度下降及腎無功能。結(jié)果與正常對(duì)照組比較,中、重度積水組患側(cè)腎GFR降低,輕、中、重度積水組健側(cè)腎GFR升高,中、重度積水組雙腎GFR降低(P均0.05)。輕度積水組90.48%的患腎GFR正常,中度積水組63.64%的患腎GFR輕度下降,重度積水組35.25%的患腎GFR重度下降、33.33%的患腎無功能。積水越嚴(yán)重腎功能越差。結(jié)論 Gates法計(jì)算的單腎、總腎GFR可定量分析單側(cè)腎積水患者腎小球?yàn)V過功能,同步評(píng)價(jià)健側(cè)腎的代償能力。
[Abstract]:Objective to investigate the value of glomerular filtration rate (GFR) calculated by Gates method in evaluating glomerular filtration function in patients with unilateral hydronephrosis. Methods 176 patients with unilateral hydronephrosis (21 mild hydronephrosis and 33 moderate hydronephrosis) were selected. There were 122 patients with severe hydronephrosis and 22 donors with normal urinary system and GFR (normal control group). Both groups received 99mTc-DTPA renal dynamic imaging. The GFR values of affected kidney, healthy kidney and double kidney were calculated by Gates method. According to the single kidney GFR, the patients were divided into normal renal function, mild decline, moderate decline, severe decline and renal failure. Results compared with the normal control group, the patients with moderate and severe hydronephrosis had lower, mild and moderate renal GFR. In the severe hydronephrosis group, the GFR of the healthy kidney increased, while in the moderate and severe hydronephrosis group, the GFR of both kidneys decreased (P < 0.05). The GFR of the affected kidney in the mild hydronephrosis group (90.48%) was normal, while that in the moderate hydronephrosis group (63.64%) was slightly decreased. In severe hydronephrosis group (35.25%), GFR decreased significantly by 33.33%. The more severe hydronephrosis, the worse the renal function. Conclusion Gates method can quantitatively analyze glomerular filtration function in patients with unilateral hydronephrosis, and total renal GFR can be used to quantify glomerular filtration function in patients with unilateral hydronephrosis. The compensatory ability of healthy kidney was evaluated simultaneously.
【作者單位】： 三峽大學(xué)第一臨床醫(yī)學(xué)院·宜昌市中心人民醫(yī)院;南京大學(xué)醫(yī)學(xué)院附屬鼓樓醫(yī)院;
【基金】：南京市醫(yī)學(xué)科技發(fā)展項(xiàng)目(YKK13063)
【分類號(hào)】：R692.2

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 任海濱,邢昌贏;腎小球?yàn)V過功能的評(píng)估[J];國(guó)外醫(yī)學(xué).泌尿系統(tǒng)分冊(cè);2005年S1期

2 馮秋霞;孫桂榮;;腎小球?yàn)V過功能的檢測(cè)方法及其研究進(jìn)展[J];中國(guó)醫(yī)刊;2007年02期

3 馮彬;王煜華;王如;孫濱;;用血清半胱氨酸蛋白酶抑制劑C評(píng)價(jià)腎小球?yàn)V過功能的研究[J];中外醫(yī)療;2009年34期

4 吳世木;錢耀先;秦苑;吳海嬰;張迪;華東;楊葉虹;;血清半胱氨酸蛋白酶抑制劑C評(píng)價(jià)糖尿病患者腎小球?yàn)V過功能的臨床價(jià)值[J];實(shí)用醫(yī)學(xué)雜志;2013年11期

5 李萍,趙瑩,余霆;肌酐在腎小球?yàn)V過功能損傷診斷中的價(jià)值的系統(tǒng)評(píng)價(jià)[J];中國(guó)循證醫(yī)學(xué)雜志;2004年11期

6 鄭淑蓓;徐曉杰;王紅;徐玉蘭;;血清半胱氨酸蛋白酶抑制劑C在評(píng)價(jià)老年患者腎小球?yàn)V過功能中的價(jià)值[J];浙江臨床醫(yī)學(xué);2007年12期

7 陳曉農(nóng);史浩;朱杰;倪莉燕;張文;王偉銘;潘曉霞;陳楠;;血清β痕跡蛋白對(duì)腎小球?yàn)V過功能的評(píng)估[J];腎臟病與透析腎移植雜志;2008年01期

8 陳云爽;孫雪峰;;腎小球?yàn)V過功能的評(píng)價(jià)方法研究進(jìn)展[J];中國(guó)實(shí)用內(nèi)科雜志;2008年10期

9 張步清;;血清胱抑素C對(duì)腎小球?yàn)V過功能損傷的診斷價(jià)值評(píng)價(jià)[J];臨床醫(yī)藥實(shí)踐;2012年12期

10 戰(zhàn)玉喜;李建新;張峰;王均梅;鄭楠;;血清半胱氨酸蛋白酶抑制劑C對(duì)腎小球?yàn)V過功能受損的臨床意義[J];診斷學(xué)理論與實(shí)踐;2006年05期

相關(guān)會(huì)議論文 前2條

1 陳曉農(nóng);史浩;倪莉燕;王朝暉;張文;王偉銘;陳楠;;應(yīng)用血β痕跡蛋白測(cè)定評(píng)價(jià)腎小球?yàn)V過功能[A];2007年浙滬兩地腎臟病學(xué)術(shù)年會(huì)資料匯編[C];2007年

2 李琮輝;;腎小球?yàn)V過功能研究的某些進(jìn)展[A];貴州省醫(yī)學(xué)會(huì)腎臟病學(xué)分會(huì)2008年學(xué)術(shù)年會(huì)論文匯編[C];2008年

相關(guān)碩士學(xué)位論文 前1條

1 景士珍;胱抑素C評(píng)估慢性腎臟病腎功能損害的臨床研究[D];新疆醫(yī)科大學(xué);2011年

，

本文編號(hào)：1574527