本文選題：漢族　切入點(diǎn)：維吾爾族　出處：《新疆醫(yī)科大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：探討新疆烏魯木齊市維漢人群高尿酸血癥(HUA)的患病情況及研究HUA與慢性腎臟病(CKD)的關(guān)系。方法：采用橫斷面調(diào)查方法,調(diào)查就診于新疆醫(yī)科大學(xué)第一附屬醫(yī)院2009年1月至2010年4月健康體檢的10025例人群和在2011年3月至2012年2月住院的982例患者,進(jìn)行回顧性分析,通過行HUA及相關(guān)危險(xiǎn)因素和相關(guān)血尿指標(biāo)檢測,結(jié)果：在資料完整的10025名體檢人群中,HUA的患病率為14.85%,CKD的患病率為9.60%,其中HUA組CKD的患病率為11.63%,明顯高于血尿酸正常組；HUA組蛋白尿的患病率為6.66%,明顯高于血尿酸正常組；HUA組eGFR下降的患病率為5.21%,明顯高于血尿酸正常組；而兩組血尿的發(fā)病率沒有明顯統(tǒng)計(jì)學(xué)差異。多因素Logistic回歸提示,HUA(OR=1.36,95%CI=1.13～1.65)、性別(OR=1.44,95%CI=1.25～1.67).收縮壓≥140mmHg(OR=1.78,95%CI=1.49～2.73)、高血糖(OR:1.36,95%CI=1.67～2.58)是CKD重要危險(xiǎn)因素。在982例住院患者中,HUA的患病率為25.46%,其中漢族740人,HUA患病率為26.62%,維族242人,HUA患病率為21.90%,漢族高于維族,差異有統(tǒng)計(jì)學(xué)意義。漢族和維族蛋白尿構(gòu)成比為(19.46%比22.70%)、eGFR下降構(gòu)成比為(4.86%比6.20%)、CKD的構(gòu)成比為(22.70%比26.03%),維族均高于漢族,差異無統(tǒng)計(jì)學(xué)意義。結(jié)論：烏魯木齊市健康體檢人群中,HUA的患病率為14.85%,CKD患病率為9.6%,住院病人,HUA的患病率為25.46%,漢族HUA患病率高于維族,差異有統(tǒng)計(jì)學(xué)意義,漢族與維族CKD患病率無統(tǒng)計(jì)學(xué)差異,高尿酸血癥、性別、年齡、收縮壓≥140mmHg、高血糖是CKD重要危險(xiǎn)因素。
[Abstract]:Objective: to investigate the prevalence of hyperuricemia (Hu) in Uygur and Han people in Urumqi, Xinjiang, and to study the relationship between HUA and chronic kidney disease (CKD). A retrospective analysis was carried out on 10025 patients who underwent physical examination in the first affiliated Hospital of Xinjiang Medical University from January 2009 to April 2010 and 982 patients who were hospitalized from March 2011 to March 2011. HUA, related risk factors and related hematuria indexes were detected. Results: in 10025 healthy people with complete data, the prevalence rate of HUA was 14.85CKD was 9.600.The prevalence rate of CKD in HUA group was 11.63, which was significantly higher than that in normal blood uric acid group (6.66g), which was significantly higher than that in normal serum uric acid group. The prevalence of eGFR decrease in the Hua group was 5.21, which was significantly higher than that in the normal serum uric acid group. However, there was no significant difference in the incidence of hematuria between the two groups. Multivariate Logistic regression suggested that 1.3695 CII 1.131.65, gender OR1.4495 CI 1.251.67, systolic blood pressure 鈮，

本文編號(hào)：1568303