本文關(guān)鍵詞： 納米細菌 上尿路結(jié)石 腎盂尿液 結(jié)石成分　出處：《石河子大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:探討納米細菌(nanobacteria,NB)在上尿路結(jié)石患者腎臟中的感染情況及兩者的相關(guān)性。方法:選取單側(cè)腎結(jié)石患者27例,分別采集患側(cè)及健側(cè)腎盂尿液,正常對照者27例采集其中段晨尿,分別進行NB的培養(yǎng),應(yīng)用茜素紅染色、掃描電鏡、免疫熒光等方法對培養(yǎng)的NB予以觀察和鑒定,比較結(jié)石患者和正常對照者納米細菌的感染情況,以及單側(cè)結(jié)石患者健側(cè)和患側(cè)腎臟納米細菌感染情況,同時分析結(jié)石成分,探討其與納米細菌的關(guān)系。結(jié)果:27名單側(cè)上尿路結(jié)石患者患側(cè)腎盂尿液樣本(27例)中有22例(81.5%)NB培養(yǎng)陽性,健側(cè)腎盂尿液樣本(22例)有9(40.9%)例NB培養(yǎng)陽性,兩者間差距有顯著統(tǒng)計學(xué)意義(χ2=8.586,P=0.003)。正常對照組27例中段尿樣本中6例(22.2%)培養(yǎng)NB陽性,與結(jié)石組患側(cè)腎盂尿樣本NB陽性率比較差異有統(tǒng)計學(xué)意義(χ2=18.989,P0.001)。18例上尿路結(jié)石中,結(jié)石成分以草酸鈣結(jié)石與碳酸磷灰石混合性結(jié)石為主約占55.6%,其次為純草酸鈣結(jié)石,約為38.9%。結(jié)論:納米細菌感染與上尿路結(jié)石發(fā)生具有一定相關(guān)性,并且納米細菌在泌尿系結(jié)石的發(fā)展中可能具有病因?qū)W作用。
[Abstract]:Objective: to investigate the relationship between the infection of nanobacteriae and NB in the kidney of patients with upper urinary tract calculi. Methods: 27 patients with unilateral renal calculi were selected. Urine samples were collected from the affected and healthy renal pelvis, and 27 cases of normal control were collected. NB culture was carried out respectively. Alizarin red staining was used and scanning electron microscope (SEM) was used. The cultured NB was observed and identified by immunofluorescence. The infection of nanobacteria in patients with calculi and normal controls and in healthy and affected kidneys of patients with unilateral calculi were compared. Results among the 27 cases of urolithiasis on the upper side of the list, 22 cases were positive for NB culture. In 22 cases of renal pelvis and urine, 9 cases were positive for NB culture, and the difference between them was statistically significant (蠂 2 = 8.586). In normal control group, 6 of 27 cases of urine samples were positive for NB. There was significant difference in NB positive rate between the patients with calculi and the patients with calculi (蠂 2 + 18.989) (P 0.001). 18 cases with upper urinary calculi. Calcium oxalate stone and carbonate apatite mixed stone accounted for 55.6%, followed by pure calcium oxalate stone. Conclusion: there is a certain correlation between the infection of nanometer bacteria and the occurrence of upper urinary tract stones, and the nanometer bacteria may play an etiological role in the development of urinary calculi.
【學(xué)位授予單位】：石河子大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R691.4

【參考文獻】

相關(guān)期刊論文 前3條

1 方克偉;程傳賢;李澤惠;徐鴻毅;;泌尿外科技術(shù)的進展與應(yīng)用[J];醫(yī)學(xué)與哲學(xué)(臨床決策論壇版);2007年07期

2 E. Olavi Kajander,Neva Ciftcioglu;Detection of nanobacteria in serum, bile and gallbladder mucosa of patients with cholecystolithiasis[J];Chinese Medical Journal;2005年05期

3 錢彪;王勤章;丁國富;鄭麗英;;載脂蛋白E基因多態(tài)性與新疆南部維吾爾族泌尿系結(jié)石相關(guān)性的研究[J];中國現(xiàn)代醫(yī)學(xué)雜志;2013年24期

，

本文編號：1469659