青少年與青壯年患者蛛網(wǎng)膜下腔阻滯麻醉中羅哌卡因半數(shù)有效量的比較
發(fā)布時間:2019-07-20 20:14
【摘要】:目的比較青少年與青壯年患者蛛網(wǎng)膜下腔阻滯麻醉中羅哌卡因的半數(shù)有效量(ED_(50))。方法隨機選取于膝關節(jié)鏡下行半月板切除術的44例患者,青少年(10~16歲,青少年組)和青壯年(18~35歲,青壯年組)各22例。所有患者均行羅哌卡因蛛網(wǎng)膜下腔阻滯麻醉,蛛網(wǎng)膜下腔阻滯麻醉的有效標準:1蛛網(wǎng)膜下腔阻滯麻醉后20min感覺阻滯平面至少達到T_(12)水平;2運動阻滯以蛛網(wǎng)膜下腔阻滯麻醉后20min雙下肢阻滯達到Bromage評分2級和2級以上;3蛛網(wǎng)膜下腔阻滯麻醉后≥60min,硬脊膜外腔中不追加局部麻醉藥物,直至手術完成。根據(jù)序貫法公式計算兩組患者羅哌卡因的ED_(50)和95%CI。結果青少年組的年齡、身高、體重均顯著低于青壯年組(P值均0.01)。青少年組的ED_(50)和95%CI為8.61(8.23~8.98)mg,青壯年組為11.35(10.97~11.72)mg。青少年組ED_(50)/青壯年組ED_(50)為0.76。結論青少年患者蛛網(wǎng)膜下腔阻滯麻醉中羅哌卡因的ED_(50)較青壯年組患者減少約24%。
[Abstract]:Objective to compare the half effective dose of ropivacaine (ED_ 50).) in subarachnoid block anesthesia between adolescents and young adults. Methods 44 patients undergoing meniscus resection under knee arthroscopy were randomly selected, including 22 adolescents (10 鈮,
本文編號:2516891
[Abstract]:Objective to compare the half effective dose of ropivacaine (ED_ 50).) in subarachnoid block anesthesia between adolescents and young adults. Methods 44 patients undergoing meniscus resection under knee arthroscopy were randomly selected, including 22 adolescents (10 鈮,
本文編號:2516891
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