胸椎旁神經(jīng)阻滯復(fù)合術(shù)畢繼續(xù)瑞芬太尼泵注對全麻患者術(shù)后雙腔氣管拔管不良反應(yīng)的預(yù)防效果
[Abstract]:Objective to observe the preventive effect of remifentanil pump on patients with double lumen extubation after endotracheal intubation. Methods 90 patients undergoing thoracotomy under general anesthesia and double lumen endotracheal intubation were randomly divided into control group (group C), remifentanil low dose group (R1 group) and remifentanil high dose group (R2 group) with 30 cases in each group. After general anesthesia and double lumen endotracheal intubation, ropivacaine thoracic paravertebrospinal nerve block was performed under the guidance of ultrasound before the operation began. Propofol, remifentanil and rocuronium were given during operation to maintain anesthesia. At the beginning of suture incision, remifentanil 0.2 渭 g / group and 0.3 渭 g / (kg 路min),) were injected with remifentanil 0.2 渭 g / (remifentanil 路min),) and equal dose sodium chloride injection respectively in group R1 and R2 respectively. The occurrence of cough before and during extubation, extubation knowledge, extubation comfort, awake time and extubation time were recorded. The BP,HR,RR,SpO_2. of patients was monitored before anesthesia, 1 min, before extubation, 2 min, after extubation, 5 min, after extubation, 10 min, after extubation, and 15 min after extubation. Visual simulated pain score (VAS), was performed at 5, 10, 20, 30 and 60 min after extubation, and Riker sedation and restlessness score (SAS). Was performed at 5, 10, 10, 15 min after extubation, respectively. Follow-up on the second day after operation was followed up to record the incidence of headache, nausea and vomiting, urinary retention and pruritus. Results in group C, R1 and R2, the cough reaction, extubation knowledge and extubation discomfort decreased in turn, and the awake time and extubation time were prolonged in turn (P 0.05). Compared with before anesthesia, the systolic blood pressure, diastolic blood pressure and HR in group C and R1 were increased at 1 min, before extubation and 5 min after extubation at 2 min after extubation (all P 0.05), and the systolic blood pressure (SBP), diastolic blood pressure (DBP) and diastolic blood pressure (HR) were increased in group C and R1 immediately before extubation. Compared with before anesthesia, RR decreased at 1 min, extubation in RI group. Compared with before anesthesia, the RR of group R2 was decreased at 1 min, before extubation and 5 min after extubation at 2 min after extubation. VAS in group R1 was lower than that in group C at 5 min after extubation. SAS in R2 group was lower than that in C group at 2 min after extubation, and the incidence of nausea and vomiting in R2 group was higher than that in C group (P 0.05). Conclusion continuous remifentanil infusion can reduce the incidence of adverse reactions related to double lumen extubation in patients with general anesthesia, improve the comfort of extubation and provide good postoperative analgesia. The effect of remifentanil 0.3 渭 g / (kg 路min) is better than that of 0.2 渭 g / (kg 路min), but the awake time and extubation time of the patients will be prolonged, which will also slow down the RR of some patients, so it is necessary to master the time of withdrawal of general anesthetics. And closely monitor RR and SpO_2..
【作者單位】: 昆明醫(yī)科大學(xué)第一附屬醫(yī)院;
【分類號(hào)】:R614.2
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