發(fā)布時間：2019-05-15 05:11

【摘要】：目的觀察靜脈注射丁丙諾啡-咪唑安定輔助硬膜外麻醉時的鎮(zhèn)靜、消除內(nèi)臟牽拉反應效果和對呼吸、循環(huán)的影響。方法硬膜外麻醉下行下腹部手術患者40例,隨機分為B組(丁丙諾啡0.15mg+咪唑安定4mg為1U)和F組(芬太尼0.1mg+咪唑安定4mg為1U),每組20例。手術開始前5min靜脈緩慢注射輔助藥物3/4-1U。觀察并記錄用藥時和用藥后5、15、30min平均動脈壓、心率、脈搏血氧飽和度和呼吸頻率,以及患者鎮(zhèn)靜程度和術中發(fā)生的牽拉反應。結果 B組的鎮(zhèn)靜、消除內(nèi)臟牽拉反應的作用明顯強于F組(P0.05);兩組對循環(huán)及呼吸均無明顯影響(P0.05)。結論丁丙諾啡-咪唑安定能安全地輔助于硬膜外麻醉,能有效的增強鎮(zhèn)靜和消除內(nèi)臟牽拉反應,對呼吸和循環(huán)無明顯影響。
[Abstract]:Objective to observe the sedation of buprenorphine midazolam assisted epidural anesthesia and to eliminate the effect of visceral traction and respiration and circulation. Methods 40 patients undergoing lower abdominal surgery under epidural anesthesia were randomly divided into group B (buprenorphine 0.15mg midazolam 4mg 1U) and group F (fentanyl 0.1mg midazolam 4mg 1U) with 20 patients in each group. Before the beginning of the operation, 5min was slowly injected intravenously with 3 脳 4 脳 1 U 路L ~ (- 1) g 路L ~ (- 1). The mean arterial pressure, heart rate, pulse oxygen saturation and respiratory rate, sedation degree and intraoperative traction reaction were observed and recorded at 15, 15 and 30 min after treatment. Results the sedation and elimination of visceral traction reaction in group B were significantly stronger than those in group F (P 0.05), but there was no significant effect on circulation and respiration in group B (P 0.05). Conclusion buprenorphine midazolam can safely assist epidural anesthesia, can effectively enhance sedation and eliminate visceral traction reaction, and has no significant effect on respiration and circulation.
【作者單位】： 福建省福鼎市醫(yī)院麻醉科;
【分類號】：R614.42
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本文編號：2477334