目標(biāo)導(dǎo)向的液體治療在全麻復(fù)合硬膜外麻醉的老年患者結(jié)腸癌根治術(shù)中的應(yīng)用
發(fā)布時(shí)間:2019-03-12 13:08
【摘要】:目的:探討以SVV作為監(jiān)測(cè)指標(biāo)的目標(biāo)導(dǎo)向液體治療在全麻復(fù)合硬膜外麻醉的老年患者結(jié)腸癌根治術(shù)中的指導(dǎo)作用。方法:擇期行結(jié)腸癌手術(shù)的老年患者60例,ASAⅡ或Ⅲ級(jí),在全麻復(fù)合硬膜外麻醉下,隨機(jī)分為SVV組(S組)和CVP組(C組)。所有患者局麻下行頸內(nèi)靜脈穿刺。S組連接Flotrac/Vigileo監(jiān)測(cè)系統(tǒng)監(jiān)測(cè)每搏變異度(SVV),將SVV≤13%,MAP≥65mmHg作為目標(biāo),行目標(biāo)導(dǎo)向液體治療;C組根據(jù)CVP及MAP行經(jīng)典補(bǔ)液治療。所有患者在麻醉誘導(dǎo)前(T0),手術(shù)開始后1h(T_1),2h(T_2)及手術(shù)結(jié)束時(shí)(T_3)記錄血流動(dòng)力學(xué)指標(biāo)及血乳酸水平,記錄術(shù)中出入量及去氧腎上腺素的應(yīng)用、術(shù)后ICU停留時(shí)間和術(shù)后并發(fā)癥等情況。結(jié)果:與C組相比,S組輸注的液體總量明顯減少[2114±503ml vs 2538±425ml,P0.05],但是膠體液量增多(956±226ml vs 618±167ml,P0.05),S組的血流動(dòng)力學(xué)更穩(wěn)定,各時(shí)點(diǎn)的血乳酸水平也較C組明顯降低。S組的術(shù)后ICU停留時(shí)間明顯縮短(4.2±1.3hvs 6.7±1.2h,P0.05),惡心、嘔吐發(fā)生率也明顯降低(13.3%vs 20.0%,P0.05)。結(jié)論:以SVV為監(jiān)測(cè)指標(biāo)的目標(biāo)導(dǎo)向液體治療(GDFT),用于全麻復(fù)合硬膜外麻醉的老年結(jié)腸癌根治術(shù)患者,可以滿足其個(gè)體化的液體治療,減少液體輸注總量,提供更平穩(wěn)的血流動(dòng)力學(xué),降低血乳酸水平,減少術(shù)后并發(fā)癥的發(fā)生率。
[Abstract]:Aim: to investigate the guiding role of target-directed liquid therapy with SVV as a monitoring index in radical resection of colon cancer in elderly patients undergoing general anesthesia combined with epidural anesthesia. Methods: 60 elderly patients undergoing elective colon cancer surgery, ASA 鈪,
本文編號(hào):2438806
[Abstract]:Aim: to investigate the guiding role of target-directed liquid therapy with SVV as a monitoring index in radical resection of colon cancer in elderly patients undergoing general anesthesia combined with epidural anesthesia. Methods: 60 elderly patients undergoing elective colon cancer surgery, ASA 鈪,
本文編號(hào):2438806
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