不同劑量地佐辛聯(lián)合丙泊酚用于門診無(wú)痛胃鏡檢查的麻醉效果觀察
[Abstract]:Objective to compare the anesthetic effects of different doses of dizosin combined with propofol for painless gastroscopy in outpatient clinic and to explore the reasonable dose of dizosin. Methods A total of 100 patients undergoing gastroscopy and agreeing to intravenous anesthesia were randomly divided into two groups: group D _ (1) D _ (2) D _ (2) D _ (3) and D _ (1) group (n = 25) were given dizosin 50ugr / kg ~ (2) D _ (2) group, and group D _ (3) were given propofol 1~2mg/kg (n = 25) by 100mg/min intravenous injection. After the eyelash reflex disappeared, the examination was performed. Propofol 20~50mg/ was added according to the patient's examination. The mitogen, heart rate (HR) and ejection oxygen saturation (SpO_2), the time of propofol to mascara disappearance, the time of gastroscopy, and the total amount of propofol were compared between the four groups at the time of entry (T0), the disappearance of mascara reflex (T1), the end of examination (T2), the heart rate (HR) and oxygen saturation of ejection (SpO_2). Awake time (time to stop giving propofol to open eyes after examination), time to leave recovery room (time between end of check and leave recovery room). The adverse reactions such as restlessness, respiratory depression and postoperative nausea and vomiting were observed in 4 groups of patients treated with propofol. Results there was an interaction between the time and method of MAPMA-HRO2 (P0.05). The difference was statistically significant (P0.05). The MAP of D1 group was lower than that of D2D3 group at T1 when MAP was lower than that of D2D3 group (P0.05). The difference was statistically significant (P0.05) the SpO_2 of group F was lower than that of group D _ 1D _ 2 / D _ 3 at T _ 1 (P0.05). The total usage of propofol in group D _ 1 was longer than that in group D _ 3 (P 0.05), and the waking time of group D _ (3) was longer than that of group D _ (3). The difference was statistically significant (P0.05) the time of disappearance of eyelash reflex, the time of gastroscope examination and the time of leaving the recovery room were not significantly different (P0.05) .Group F had no significant difference when the patients were given propofol. The incidence of postoperative nausea and vomiting was higher than that of the other three groups, the difference was statistically significant (P 0.05,) .4 patients had no serious complications. Conclusion 100ug/kg dizosin combined with propofol is an appropriate dose for the treatment of outpatient painless gastroscopy with less adverse reactions such as respiratory depression nausea and vomiting restlessness stable hemodynamics and no prolongation of recovery time.
【作者單位】: 武警內(nèi)蒙古總隊(duì)醫(yī)院麻醉科;
【分類號(hào)】:R614
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