不同濃度七氟醚對(duì)老年冠心病患者麻醉誘導(dǎo)期心率變異性的影響
發(fā)布時(shí)間:2018-07-31 09:07
【摘要】:目的探討七氟醚對(duì)老年冠心病患者在全麻誘導(dǎo)期心率變異性(HRV)的影響。方法 40例擇期行上腹部手術(shù)老年冠心病患者,美國(guó)麻醉醫(yī)生協(xié)會(huì)(ASA)Ⅱ~Ⅲ級(jí)。隨機(jī)分為低濃度組和高濃度組,每組20例。麻醉誘導(dǎo)開(kāi)始時(shí),緩慢靜脈推注芬太尼3μg/kg,吸入6 L/min氧氣及七氟醚,維持七氟醚的呼氣末濃度在預(yù)定值(低濃度組為2.0 Vol%,高濃度組為4.0 Vol%),當(dāng)意識(shí)和睫毛反射消失后,靜注維庫(kù)溴胺0.1 mg/kg,行氣管插管。記錄麻醉前基礎(chǔ)值及誘導(dǎo)后5、10、15、20 min的收縮壓(SBP)、舒張壓(DBP)、心率(HR)、心率變異性(HRV),并記錄各組肌僵、嗆咳、低血壓等副反應(yīng)的發(fā)生情況。結(jié)果 2組患者的SBP、DBP在誘導(dǎo)后5、10 min顯著下降(P0.05),高濃度組下降較低濃度組明顯(P0.05),其后患者的血壓漸趨平穩(wěn),2組心率無(wú)顯著變化(P0.05)。在麻醉誘導(dǎo)中,2組低頻(LF)和低頻/高頻(LF/HF)逐漸降低,而HF均沒(méi)有明顯的變化,其中高濃度組比低濃度組對(duì)HRV各參數(shù)的影響都較明顯。結(jié)論老年冠心病患者用七氟醚吸入麻醉誘導(dǎo)主要抑制心臟交感神經(jīng)活性,并呈劑量依賴性,對(duì)血流動(dòng)力學(xué)影響較輕,誘導(dǎo)相對(duì)平穩(wěn),適合老年冠心病患者的麻醉誘導(dǎo)。
[Abstract]:Objective to investigate the effect of sevoflurane on heart rate variability (HRV) in elderly patients with coronary heart disease during induction of general anesthesia. Methods 40 elderly patients with coronary heart disease undergoing epigastric surgery were enrolled in this study. The American Association of Anesthesiologists, (ASA) 鈪,
本文編號(hào):2155101
[Abstract]:Objective to investigate the effect of sevoflurane on heart rate variability (HRV) in elderly patients with coronary heart disease during induction of general anesthesia. Methods 40 elderly patients with coronary heart disease undergoing epigastric surgery were enrolled in this study. The American Association of Anesthesiologists, (ASA) 鈪,
本文編號(hào):2155101
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