本文選題：面口合谷收 + 感覺皮層�。� 參考：《廣州中醫(yī)藥大學(xué)》2014年碩士論文

【摘要】：目的： 觀察合谷穴區(qū)去感覺傳入后恒河猴軀體感覺皮層手區(qū)和面區(qū)的可塑性,探討“面口合谷收”的生物學(xué)機制。 方法： 切斷恒河猴正中神經(jīng)和橈神經(jīng)后,用針刺方式刺激麻醉狀態(tài)下恒河猴的合谷穴區(qū)和面口部,記錄軀體感覺皮層神經(jīng)元的放電活動,并勾畫其外周感受野,比較切斷正中神經(jīng)和橈神經(jīng)前后外周感受野的變化。 成果： 在恒河猴軀體感覺皮層S1區(qū)共記錄A到N共14個通道神經(jīng)元的感受野。切斷正中神經(jīng)和橈神經(jīng)前,通道A至E的神經(jīng)元感受野為手部區(qū)域,通道F至N的神經(jīng)元感受野均為面部。通道A的神經(jīng)元感受野為手背側(cè)拇指根部至指尖；通道B、D的神經(jīng)元感受野均為手掌側(cè)大魚際；通道C的神經(jīng)元感受野為手掌側(cè)拇指、食指根部至指尖；通道E的神經(jīng)元感受野為手掌側(cè)拇指根部至指尖；通道F、G、H的神經(jīng)元感受野均為面部左側(cè)唇以下頦肌、降下唇肌覆蓋的部位；通道K、Ⅰ的神經(jīng)元感受野均為面部左側(cè)鼻旁鼻肌、提上唇肌覆蓋的區(qū)域；通道J、L的神經(jīng)元感受野均為面部左側(cè)頰肌、腮腺管覆蓋區(qū)域；通道M、N的神經(jīng)元感受野均為面部左側(cè)咬肌、降口角肌、降下唇肌覆蓋區(qū)域。 正中神經(jīng)和橈神經(jīng)切斷后1小時后,通道A、B、C、D、E、F的神經(jīng)元對手部刺激不起反應(yīng),其余通道的感受野未發(fā)生變化。 切斷后7小時,通道A、B、C、D的神經(jīng)元對手部刺激不起反應(yīng)；通道E得神經(jīng)元感受野為手掌側(cè)拇指根部至指尖轉(zhuǎn)變?yōu)槊娌孔髠?cè)唇以下頦肌、降下唇肌覆蓋的部位；其余通道的神經(jīng)元感受野未發(fā)生變化。 切斷后24小時,通道A、B的神經(jīng)元對手部刺激不起反應(yīng)；通道C、D、E的神經(jīng)元感受野均由切斷前的區(qū)域轉(zhuǎn)變?yōu)槊娌孔髠?cè)唇以下頦肌、降下唇肌覆蓋的部位；其余通道的感受野未發(fā)生變化。 結(jié)論： 合谷穴區(qū)去感覺傳入后,軀體感覺皮層面區(qū)向手區(qū)進行了極小的擴張,手區(qū)和面區(qū)發(fā)生了重組,體表與體表的特定聯(lián)系更加突出,與腦可塑性密切相關(guān)。這可能是病理狀況下“面口合谷收”的生物學(xué)機制之一。
[Abstract]:Objective: To observe the plasticity of hand and facial regions of somatosensory cortex in rhesus monkey after sensory afferent in Hegu acupoint area, and to explore the biological mechanism of "face mouth and valley harvest". Methods: After the median nerve and radial nerve of rhesus monkey were cut off, the area of Hegu acupoint and the facial orifice of rhesus monkey under anesthesia were stimulated by acupuncture. The discharges of somatosensory cortical neurons were recorded, and the peripheral receptive fields were delineated. The changes of peripheral receptive field before and after transection of median nerve and radial nerve were compared. Outcome: A total of 14 channels were recorded in the S1 region of somatosensory cortex of rhesus monkeys. Before the median nerve and radial nerve were transected, the receptive field of channel A to E was the hand region, and that of channel F to N was facial. The neuronal receptive field of channel A was from the root of the dorsal thumb of the hand to the tip of the finger, the neuronal receptive field of channel BnD was the hypothenar side of the palm, and the neuronal receptive field of channel C was the thumb of the palm and the root of the forefinger to the tip of the finger. The neuronal receptive field of channel E is from the root of the palmar thumb to the fingertip, the neuronal receptive field of the channel FG H is the place covered by the lower chin muscle on the left lip of the face, and the neuronal receptive field of channel K, I are all the nasal muscles of the left side of the face. The area covered by the levator labium muscle, the area covered by the facial left buccal muscle and the parotid duct, and the area covered by the facial left masseter muscle, the descending horn muscle and the lower labial muscle were all the neuronal receptive fields of the channel Mnn were the left buccal muscle of the face and the parotid duct covered area. One hour after median nerve and radial nerve transection, the neurons of the channel Agna C ~ (2 +) D ~ (1) E _ (F) did not respond to the stimulation of the hand, but the other channels' receptive fields did not change. At 7 hours after transection, the neurons of channel Agna C ~ (2 +) could not respond to the stimulation of the hand, and the receptive field of channel E was the place where the palmar thumb was transformed from the root of the thumb to the tip of the finger to the left lip of the face to the chin muscle, which was covered by the labial muscle. There was no change in the sensory field of the other channels. At 24 hours after transection, the neurons of channel Aneb did not respond to the stimulation of the hand, and the receptive field of the neurons of channel CfU E changed from the region before the dissection to the part of the chin muscle on the left lip of the face, which was covered by the labial muscle. There was no change in the sensory field of the other channels. Conclusion: After the sensory afferent of the Hegu acupoint area, the somatosensory skin area expanded to the hand area, the hand area and the facial area were reorganized, and the specific connection between the body surface and the body surface was more prominent, which was closely related to the plasticity of the brain. This may be one of the biological mechanisms of facial constriction under pathological conditions.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R245

【參考文獻】

相關(guān)期刊論文 前10條

1 陸良;針灸治療三叉神經(jīng)痛20例臨床觀察[J];蚌埠醫(yī)藥;1995年03期

2 張麗平;袁文麗;石紅霞;;合谷刺配合面部閃罐治療頑固性面癱臨床研究[J];中醫(yī)學(xué)報;2010年05期

3 康蓮英;;面癱治療中針刺合谷穴的紅外熱像觀察[J];中外醫(yī)療;2010年21期

4 李落意;趙斌;楊駿;李傳富;徐春生;朱一芳;;“面口合谷收”神經(jīng)生理機制的fMRI研究[J];中國中西醫(yī)結(jié)合影像學(xué)雜志;2012年01期

5 張心如;體針合谷足三里合梅花針治療單純性面癱80例[J];南通醫(yī)學(xué)院學(xué)報;1996年04期

6 王詹青;;止血敏雙側(cè)合谷穴注射治療60例頑固性鼻衄的療效觀察[J];青海醫(yī)藥雜志;2006年05期

7 陳延君;孫楊;;針灸治療青少年近視眼150例臨床觀察[J];青海醫(yī)藥雜志;2009年06期

8 趙昌宋;合谷穴封閉治療牙痛[J];四川中醫(yī);1988年12期

9 陶紅星;;針刺配合拔罐治療面肌痙攣療效觀察[J];山西中醫(yī);2009年05期

10 胡曉敏;;針灸治療牙痛57例[J];上海針灸雜志;1987年03期

，

本文編號：1951522