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瑞芬太尼和芬太尼用于老年患者麻醉中的臨床對(duì)比分析

發(fā)布時(shí)間:2018-05-05 09:31

  本文選題:麻醉 + 老年。 參考:《臨床醫(yī)藥文獻(xiàn)電子雜志》2016年03期


【摘要】:目的比較瑞芬太尼和芬太尼用于老年患者麻醉中的效果。方法選取我院2012年11月~2014年11月收治的老年患者431例,將其隨機(jī)分為觀察組216例與對(duì)照組215例。所有患者均進(jìn)行常規(guī)麻醉前準(zhǔn)備,觀察組給予瑞芬太尼0.1μg/kg,對(duì)照組給予芬太尼2.0μg/kg進(jìn)行麻醉。觀察兩組患者麻醉后恢復(fù)自主呼吸及定向力的時(shí)間,蘇醒時(shí)間以及不良反應(yīng)發(fā)生情況。結(jié)果觀察組患者恢復(fù)自主呼吸、定向力的時(shí)間與對(duì)照組相比均較短,蘇醒較快,差異有統(tǒng)計(jì)學(xué)意義(P0.05);觀察組出現(xiàn)蘇醒期躁動(dòng)、惡心、嘔吐、嗆咳等不良反應(yīng)的幾率小于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);觀察組麻醉優(yōu)良率為98.1%,對(duì)照組為92.6%,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論同屬阿片受體激動(dòng)劑,與芬太尼相比,瑞芬太尼用于臨床麻醉,可明顯縮短患者恢復(fù)自主呼吸、定向力的時(shí)間,麻醉后蘇醒較快,出現(xiàn)蘇醒期躁動(dòng)、惡心、嘔吐、嗆咳等不良反應(yīng)的幾率較小,麻醉的優(yōu)良率較高,值得臨床推廣與使用。
[Abstract]:Objective to compare the effect of remifentanil and fentanyl in elderly patients. Methods from November 2012 to November 2014, 431 elderly patients were randomly divided into observation group (216 cases) and control group (215 cases). All patients were prepared for routine anesthesia. The observation group was given remifentanil 0.1 渭 g / kg and the control group was given fentanyl 2.0 渭 g/kg. The recovery time of spontaneous respiration and orientation, recovery time and adverse reaction after anesthesia were observed. Results the time of recovery of spontaneous respiration in the observation group was shorter than that in the control group, and the recovery rate of the patients in the observation group was shorter than that in the control group, and the difference was statistically significant (P 0.05), and the incidence of adverse reactions such as restlessness, nausea, vomiting and cough in the observation group was less than that in the control group. The difference was statistically significant (P 0.05), the excellent and good rate of anesthesia in the observation group was 98.1 and that in the control group was 92.6.The difference was statistically significant (P 0.05). Conclusion compared with fentanyl, remifentanil can significantly shorten the time of recovery of spontaneous respiration and orientation after anaesthesia, and remifentanil can induce restlessness, nausea and vomiting during anaesthesia. The adverse reactions such as cough are less and the excellent and good rate of anesthesia is higher, so it is worth popularizing and using in clinic.
【作者單位】: 深州市醫(yī)院麻醉科;深州市醫(yī)院檢驗(yàn)科;深州市醫(yī)院外科;
【分類號(hào)】:R614

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