本文選題：七氟烷 + 丙泊酚�。� 參考：《慢性病學(xué)雜志》2016年05期

【摘要】：目的比較兩種全身麻醉方式(七氟烷復(fù)合瑞芬太尼與丙泊酚復(fù)合瑞芬太尼)在小兒全身麻醉的應(yīng)用效果差異。方法選擇行擇期全身麻醉手術(shù)的患兒80例,隨機(jī)分為A、B兩組,各40例。A組采用七氟烷吸入復(fù)合瑞芬太尼靶控輸注麻醉,B組采用丙泊酚復(fù)合瑞芬太尼靶控輸注麻醉,A、B兩組均采用經(jīng)喉罩全身麻醉并在聽(tīng)覺(jué)誘發(fā)電位指數(shù)監(jiān)測(cè)指導(dǎo)下進(jìn)行。比較兩組患兒在進(jìn)入手術(shù)室誘導(dǎo)前(T1)、插入喉罩前(T2)、插入喉罩時(shí)(T3)、插入喉罩后(T4)、切皮時(shí)(T5)、手術(shù)15 min時(shí)(T6)、手術(shù)30 min時(shí)(T7)、手術(shù)1 h(T8)、手術(shù)結(jié)束時(shí)(T9)及出手術(shù)室時(shí)(T10)共10個(gè)時(shí)間段的心率(HR)、收縮壓(SBP)、舒張壓(DBP)、平均動(dòng)脈壓(MAP),并比較兩組患兒停止麻醉至拔除喉罩的時(shí)間及術(shù)后并發(fā)癥發(fā)生率的比例差異。結(jié)果兩組患兒的平均年齡、平均身高及體質(zhì)量、性別差異、手術(shù)類型比例等差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。而兩組的HR、SBP、DBP、MAP在T1、T2、T3、T4、T5等5個(gè)時(shí)間點(diǎn)上差異無(wú)統(tǒng)計(jì)計(jì)學(xué)意義(P0.05),而T6~T10等5個(gè)時(shí)間點(diǎn)上差異有統(tǒng)計(jì)學(xué)意義(均P0.05)。A、B兩組拔除喉罩時(shí)間無(wú)明顯差異[(12.6±4.6)vs.(13.8±5.2)min,P0.05],而A組術(shù)后并發(fā)癥的發(fā)生率(27.50%)低于B組(50.00%),差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論七氟烷復(fù)合瑞芬太尼麻醉方式較丙泊酚復(fù)合瑞芬太尼用于小兒全身麻醉具有更穩(wěn)定的術(shù)中血流動(dòng)力學(xué),術(shù)后并發(fā)癥的發(fā)生率更低的優(yōu)勢(shì)。
[Abstract]:Objective to compare the effects of two general anesthesia methods (seven fluorothane combined with propofol and propofol combined with remifentanil) in pediatric general anesthesia. Methods 80 cases of children undergoing general anesthesia were randomly divided into A, B two, 40.A group and seven fluorothane combined with remifentanil for target controlled infusion, and B in group B. The target controlled infusion of propofol combined with remifentanil, A, B two groups were conducted under the guidance of the laryngeal mask general anesthesia and the auditory evoked potential index. The two groups were compared to the operation room before induction (T1), insertion of the laryngeal mask (T2), insertion of the laryngeal mask (T3), the insertion of the laryngeal mask (T4), the skin cutting (T5), the operation 15 min (T6), and the operation 30 min (T7). The heart rate (HR), systolic pressure (SBP), diastolic pressure (DBP) and mean arterial pressure (MAP) were performed at 1 h (T8), end of operation (T9) and operation room (T10), and the ratio of the time of stopping anesthesia to extraction of larynx and the incidence of postoperative complications in the two groups were compared. Results the average age, average height and body mass of the two groups were compared. There was no statistical significance (P0.05) for the difference of sex and the proportion of surgical types, but there were no statistical significance (P0.05) in the 5 time points of the two groups, such as T1, T2, T3, T4, T5, etc. at the 5 time points of T1, T2, T3, T4, T5 and so on. There was no significant difference between the 5 time points of T6~T10 and other two groups [(12.6 + 4.6) (13.8 + 5.2). 0.05], and the incidence of postoperative complications in group A (27.50%) was lower than that in group B (50%), and the difference was statistically significant (P0.05). Conclusion seven fluorane compound remifentanil combined with propofol and remifentanil for pediatric general anesthesia has more stable intraoperative hemodynamics and lower incidence of postoperative complications.

【作者單位】： 廣州市番禺區(qū)何賢紀(jì)念醫(yī)院;
【基金】：廣東省中醫(yī)藥局基金資助項(xiàng)目(20151034)
【分類號(hào)】：R726.1

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本文編號(hào)：1797172