本文選題：右美托咪定 + 插管法�。� 參考：《解放軍醫(yī)藥雜志》2016年09期

【摘要】：目的觀察右美托咪定聯(lián)合瑞芬太尼在困難氣道患者纖維支氣管鏡氣管插管中的臨床效果。方法回顧性分析2014年1月—2015年12月行纖維支氣管鏡氣管插管的困難氣道患者100例,根據(jù)用藥方法分為觀察組和對(duì)照組各50例。兩組均給予瑞芬太尼稀釋液靜脈泵入,觀察組在此基礎(chǔ)上給予右美托咪定。比較兩組患者入室后(T0)、藥物輸注完畢(T1)、纖維支氣管鏡插管前(T2)、插管即刻(T3)、插管后5 min(T4)的平均動(dòng)脈壓(MAP)、心率(HR)、血氧飽和度(Sp O2)以及Ramsay評(píng)分,并觀察術(shù)后不良反應(yīng)情況。結(jié)果觀察組MAP、HR在T1、T2、T3時(shí)低于對(duì)照組(P0.05)。兩組Sp O2變化差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。與T0、T1比較,觀察組T2、T3、T4時(shí)Ramsay評(píng)分升高(P0.05);對(duì)照組T2、T3降低,T4時(shí)點(diǎn)升高(P0.05);且在T2、T3、T4時(shí)觀察組高于對(duì)照組(P0.05)。觀察組不良反應(yīng)發(fā)生率低于對(duì)照組(P0.05)。結(jié)論右美托咪定聯(lián)合瑞芬太尼對(duì)困難氣道患者纖支鏡插管的麻醉效果較好,安全性較高。
[Abstract]:Objective to observe the clinical effect of dexmetomidine combined with remifentanil on tracheal intubation under fibrobronchoscope in patients with difficult airway.Methods from January 2014 to December 2015, 100 cases of difficult airway intubation with fiberoptic bronchoscope were analyzed retrospectively. According to the medication methods, the patients were divided into two groups: the observation group (n = 50) and the control group (n = 50).Both groups were injected with remifentanil diluted solution via vein, and the observation group received dexmetomidine on this basis.The mean arterial pressure (MAPP), heart rate (HRT), blood oxygen saturation (SpO2) and Ramsay score were compared between the two groups. The mean arterial pressure (MAPP), heart rate (HR), blood oxygen saturation (SpO2) and Ramsay score were compared between the two groups.Results the MAPHR in the observation group was lower than that in the control group at T _ 1 and T _ 2 T _ 3.There was no significant difference in SPO 2 between the two groups (P 0.05).Compared with T0 T 1, the Ramsay score of the observation group was higher than that of the control group at T 2, T 3 and T 4, while that of the control group was higher than that of the control group at the time point of decrease of T 2 T 3 and T 4, and the observation group was higher than that of the control group at T 2 T 3 T 4.The incidence of adverse reactions in the observation group was lower than that in the control group (P 0.05).Conclusion dexmetomidine combined with remifentanil is effective and safe in the treatment of bronchofiberscope intubation in patients with difficult airway.
【作者單位】： 青島市膠州中心醫(yī)院麻醉科;
【分類號(hào)】：R614.21

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