我國(guó)老年患者術(shù)后譫妄危險(xiǎn)因素的系統(tǒng)評(píng)價(jià)
發(fā)布時(shí)間:2018-03-18 10:46
本文選題:老年人 切入點(diǎn):譫妄 出處:《中國(guó)全科醫(yī)學(xué)》2015年10期 論文類(lèi)型:期刊論文
【摘要】:目的探討我國(guó)老年患者術(shù)后譫妄的危險(xiǎn)因素,為臨床制定干預(yù)措施提供依據(jù)。方法檢索萬(wàn)方數(shù)據(jù)資源系統(tǒng)、相關(guān)期刊論文(CNKI)、維普信息資源系統(tǒng)(VIP),收集建庫(kù)至2013年12月公開(kāi)發(fā)表的關(guān)于老年患者術(shù)后譫妄危險(xiǎn)因素研究文獻(xiàn),按納入和剔除標(biāo)準(zhǔn)進(jìn)行篩選,采用Rev Man 5.2軟件對(duì)病例對(duì)照文獻(xiàn)進(jìn)行Meta分析,對(duì)病例總結(jié)文獻(xiàn)統(tǒng)計(jì)各危險(xiǎn)因素的發(fā)生率。結(jié)果共納入16篇文獻(xiàn),其中病例對(duì)照8篇,病例總結(jié)8篇。病例對(duì)照文獻(xiàn)累計(jì)病例353例、對(duì)照2 008例。老年術(shù)后譫妄各因素合并OR值(95%CI)分別為:低氧血癥2.58(1.59,4.18)、合并肺部感染4.76(1.36,16.67)、合并高血壓2.16(1.20,3.89)、合并冠心病1.50(0.82,2.73)、術(shù)后疼痛3.18(1.63,6.20)、全身麻醉3.64(0.94,14.11)、手術(shù)時(shí)間32.30(-37.67,102.27)、高齡(≥70歲)0.99(-0.46,2.45)。Meta分析結(jié)果顯示,低氧血癥、合并肺部感染、合并高血壓、術(shù)后疼痛是老年患者術(shù)后譫妄的危險(xiǎn)因素(P0.05)。病例總結(jié)文獻(xiàn)累計(jì)病例共404例,其中低氧血癥、合并高血壓的發(fā)生率較高,分別為62.6%(253例)、55.9%(226例)。結(jié)論術(shù)前合并高血壓、肺部感染,術(shù)后低氧血癥、疼痛是老年患者術(shù)后譫妄的危險(xiǎn)因素。
[Abstract]:Objective to explore the risk factors of postoperative delirium in elderly patients in China, and to provide evidence for clinical intervention. The full text database of Chinese periodicals, CNKI, Weip Information Resource system (Wip), collected and published literatures on risk factors of postoperative delirium in elderly patients until December 2013, and screened them according to the criteria of inclusion and exclusion. Rev Man 5.2 software was used for Meta analysis of case-control literature, and the incidence of risk factors in the literature was analyzed. Results 16 articles were included, 8 of which were case-control. Eight cases were summarized. The total number of cases in the case-control literature was 353. In the control group of 2 008 cases, the factors of postoperative delirium in elderly patients with OR value of 95 CI were as follows: hypoxemia 2.581.59 / 4.18, pulmonary infection 4.761.3616.67, hypertension 2.16 / 1.20 / 3.89, coronary heart disease 1.50 / 0.822.73a, postoperative pain 3.181.63 / 6.20, general anesthesia 3.644.0.94 / 14.11a, operation time 32.30-637.7/ 102.27. the results of Meta analysis showed that the aged (鈮,
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