本文選題：經(jīng)尿道前列腺電切術(shù)　切入點(diǎn)：右美托咪定　出處：《中國現(xiàn)代醫(yī)學(xué)雜志》2015年19期 　論文類型：期刊論文

【摘要】：目的分析右美托咪定與咪達(dá)唑侖復(fù)合腰硬聯(lián)合麻醉對經(jīng)尿道前列腺電切術(shù)(TURP)患者術(shù)中應(yīng)激反應(yīng)和術(shù)后認(rèn)知功能的影響。方法選擇在該院接受住院治療的TURP患者作為研究對象,隨機(jī)分為咪達(dá)唑侖復(fù)合腰硬聯(lián)合麻醉的對照組、右美托咪定復(fù)合腰硬聯(lián)合麻醉的觀察組,比較兩組患者的血清S100β水平、應(yīng)激水平及術(shù)后認(rèn)知功能等差異。結(jié)果觀察組患者接受右美托咪定復(fù)合腰硬聯(lián)合麻醉后各個時間點(diǎn)的血清S100β水平均明顯低于對照組(P0.05)。觀察組患者的應(yīng)激指標(biāo)腎上腺素(E)、去甲腎上腺素(NE)、腎素(R)以及血管緊張素Ⅱ(ATⅡ)水平均明顯低于對照組(P0.05)。觀察組患者術(shù)后各個時間點(diǎn)的認(rèn)知功能評分均明顯高于對照組(P0.05)。結(jié)論右美托咪定復(fù)合腰硬聯(lián)合麻醉可以更為有效的減輕圍術(shù)期應(yīng)激反應(yīng),減少對患者認(rèn)知功能的抑制作用。
[Abstract]:Objective to analyze the effect of combined epidural anesthesia of dexmetomidine and midazolam on stress response and postoperative cognitive function in patients undergoing transurethral resection of the prostate (TURP). They were randomly divided into two groups: the control group with midazolam combined with spinal-epidural anesthesia and the observation group with dexmetomidine combined with spinal-epidural anesthesia. The serum S100 尾 levels were compared between the two groups. Results the levels of serum S100 尾 in the observation group were significantly lower than those in the control group at all time points after dexmetomidine combined with spinal epidural anesthesia. The stress index of the observation group was superior to that of the control group (P 0.05). The levels of adenine, norepinephrine, renin and angiotensin 鈪，

本文編號：1585878