本文關(guān)鍵詞：右美托嘧啶對(duì)TURBT手術(shù)病人麻醉蘇醒期躁動(dòng)的影響　出處：《青島大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 躁動(dòng) 麻醉蘇醒期 右美托嘧啶 血流動(dòng)力學(xué)

【摘要】：目的：觀察右美托咪定對(duì)經(jīng)尿道膀胱腫瘤電切(TURBT)手術(shù)病人麻醉蘇醒期躁動(dòng)的影響。 方法：將60例行TURBT手術(shù)的患者隨機(jī)分為右美托咪定組(D組)和安慰劑組(C組),每組30例,兩組均采用全憑靜脈麻醉。在麻醉誘導(dǎo)前10min,D組泵注右美托咪定0.5μ g/kg,C組同樣方式泵注等容量的生理鹽水,分別記錄To(入室后5min)、T,(麻醉誘導(dǎo)后)、T2(膀胱鏡進(jìn)鏡后)、T3(手術(shù)開始后15min)、T4(喉罩拔出后)各時(shí)間點(diǎn)患者的HR、MAP數(shù)值及術(shù)畢病人恢復(fù)情況(首次自主呼吸時(shí)間,拔管時(shí)間,躁動(dòng)分級(jí)及發(fā)生率,以及惡心、嘔吐、嗜睡、呼吸抑制等不良時(shí)間的發(fā)生率)。 結(jié)果：D組T1時(shí)間點(diǎn)MAP、HR值與C組比較無(wú)明顯差異(P0.05),T2,T3,T4時(shí)間點(diǎn)MAP、HR值與C組比較有明顯差異(P0.05)。D組的首次自主呼吸及拔管時(shí)間較C組比較均無(wú)統(tǒng)計(jì)學(xué)差異(P0.05)；D組躁動(dòng)分級(jí)及發(fā)生率明顯低于C組(P0.05)；惡心、嘔吐、呼吸抑制及嗜睡等不良事件發(fā)生率無(wú)有顯著差異(P0.05)。 結(jié)論：麻醉誘導(dǎo)前10分鐘泵注右美托咪定0.5μ g/kg,能有效降低TURBT手術(shù)患者血流動(dòng)力學(xué)的波動(dòng),減輕病人術(shù)后躁動(dòng),對(duì)病人的蘇醒時(shí)間及拔管時(shí)間無(wú)明顯影響,且對(duì)蘇醒期不良事件的發(fā)生無(wú)明顯影響,有助于提高麻醉的安全性。
[Abstract]:Objective: To observe the effect of dexmedetomidin on the restlessness of the patients undergoing transurethral resection of bladder tumor (TURBT).
Methods: 60 cases of TURBT were randomly divided into dexmedetomidine group (D group) and placebo group (C group), 30 cases in each group, two groups were treated with intravenous anesthesia. In 10min before induction of anesthesia, group D infusion of dexmedetomidine 0.5 g/kg normal saline, C group the same way infusion volume were recorded, To (5min, T, after the burglary) (after induction of anesthesia (cystoscope), T2 T3 (in the mirror), after the start of surgery, T4 (15min) after pulling out the laryngeal mask) at each time point in patients with HR, MAP value and postoperative patients recovery the situation (for the first time of spontaneous breathing time, extubation time, and the incidence of restlessness, nausea and vomiting, lethargy, respiratory depression and other adverse time incidence).
Results: in group D, T1 time point MAP, HR values with no significant difference between the C group (P0.05), T2, T3, T4, MAP time point, HR value had significant difference compared with group C (P0.05).D group for the first time of spontaneous breathing and extubation time compared with the C group had no statistical difference (P0.05) D; group of restlessness and was significantly lower than the C group (P0.05); the incidence of nausea, vomiting, respiratory depression and lethargy and other adverse events without significant difference (P0.05).
Conclusion: 10 minutes before anesthesia, infusion of dexmedetomidine 0.5 g/kg TURBT patients can effectively reduce hemodynamic fluctuations, reduce postoperative restlessness, recovery time and pull on the patient's time had no obvious effect, and had no significant effect on the occurrence of adverse events in the recovery period, help to improve safety the anesthetic.

【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R614

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