【摘要】：目的探討血清白細胞介素(IL)-10評估不同年齡免疫功能受損并重癥肺炎患者病情嚴重程度及預后的價值。方法 180例免疫功能受損并重癥肺炎患者,根據(jù)年齡分為非老年組(年齡60歲,112例)、老年組(年齡≥60歲,68例);入院后行APACHEⅡ評分、淋巴細胞亞群及血清IL-10水平檢測;比較兩組患者病情嚴重程度及結(jié)局差異,血清IL-10表達水平差異及與病情嚴重程度的關(guān)系。結(jié)果相比于非老年組,老年組病情重,APACHEⅡ評分較高[非老年組(24.22±7.51)分,老年組(36.53±13.52)分],死亡率高(非老年組51.79%,老年組73.53%;P0.05);老年患者血清IL-10水平[(6.72±1.97)mg/dl]低于非老年組[(9.66±2.58)mg/dl,P0.05];相關(guān)性分析顯示,血清IL-10水平與APACHEⅡ評分呈負相關(guān)。結(jié)論檢測免疫受損合并重癥肺炎患者血清IL-10水平,有助于評估及預測病情嚴重程度及預后。
[Abstract]:Objective to evaluate the value of serum IL-10 in evaluating the severity and prognosis of patients with severe pneumonia with immune impairment in different ages. Methods according to age, 180 patients with severe pneumonia were divided into non-elderly group (age 60 years, 112 cases) and elderly group (age 鈮，

本文編號：2517099