【摘要】：目的探討血清白細(xì)胞介素(IL)-10評(píng)估不同年齡免疫功能受損并重癥肺炎患者病情嚴(yán)重程度及預(yù)后的價(jià)值。方法 180例免疫功能受損并重癥肺炎患者,根據(jù)年齡分為非老年組(年齡60歲,112例)、老年組(年齡≥60歲,68例);入院后行APACHEⅡ評(píng)分、淋巴細(xì)胞亞群及血清IL-10水平檢測(cè);比較兩組患者病情嚴(yán)重程度及結(jié)局差異,血清IL-10表達(dá)水平差異及與病情嚴(yán)重程度的關(guān)系。結(jié)果相比于非老年組,老年組病情重,APACHEⅡ評(píng)分較高[非老年組(24.22±7.51)分,老年組(36.53±13.52)分],死亡率高(非老年組51.79%,老年組73.53%;P0.05);老年患者血清IL-10水平[(6.72±1.97)mg/dl]低于非老年組[(9.66±2.58)mg/dl,P0.05];相關(guān)性分析顯示,血清IL-10水平與APACHEⅡ評(píng)分呈負(fù)相關(guān)。結(jié)論檢測(cè)免疫受損合并重癥肺炎患者血清IL-10水平,有助于評(píng)估及預(yù)測(cè)病情嚴(yán)重程度及預(yù)后。
[Abstract]:Objective to evaluate the value of serum IL-10 in evaluating the severity and prognosis of patients with severe pneumonia with immune impairment in different ages. Methods according to age, 180 patients with severe pneumonia were divided into non-elderly group (age 60 years, 112 cases) and elderly group (age 鈮，

本文編號(hào)：2517099