神經(jīng)調(diào)節(jié)輔助通氣在重癥創(chuàng)傷性濕肺合并ARDS患者中的應(yīng)用
發(fā)布時(shí)間:2019-06-07 10:58
【摘要】:目的:探索在重癥創(chuàng)傷性濕肺(STWL)患者中應(yīng)用神經(jīng)電活動(dòng)輔助通氣(NAVA)模式與傳統(tǒng)壓力支持通氣(如PSV)模式相比較時(shí),其人機(jī)同步性、呼吸力學(xué)、氣體交換能力、血流動(dòng)力學(xué)上的差異。方法:以18例需機(jī)械通氣的重癥創(chuàng)傷性濕肺患者為研究對(duì)象,每例患者隨機(jī)先任選NAVA或PSV模式進(jìn)行機(jī)械通氣120min,再換用另一種通氣模式。比較同一患者在兩種通氣模式下,其人機(jī)同步性、呼吸力學(xué)、氣體交換能力、血流動(dòng)力學(xué)等方面的不同。結(jié)果:18例患者的血流動(dòng)力學(xué)(HR、CVP)及氣體交換能力(動(dòng)脈血pH值、PaO2、PaCO2、SaO2)在兩種模式間無(wú)明顯差異(P0.05),在人機(jī)同步性(Trigger delay、Off cycle delay)及呼吸力學(xué)(PIP、Pmean)方面NAVA優(yōu)于PSV,差異具有顯著性(P0.05)。結(jié)論:對(duì)于重癥創(chuàng)傷性濕肺機(jī)械通氣患者,NAVA模式比PSV模式,具有人機(jī)協(xié)調(diào)性高、呼吸力學(xué)穩(wěn)定等優(yōu)勢(shì),而在血流動(dòng)力學(xué)及氣體交換能力上具有相似的安全性。
[Abstract]:Objective: to explore the man-machine synchronization, respiratory mechanics and gas exchange ability of neuroelectrical activity-assisted ventilation (NAVA) model compared with traditional pressure-supported ventilation (such as PSV) mode in patients with severe traumatic wet lung (STWL). Hemodynamic differences. Methods: 18 patients with severe traumatic wet lung who needed mechanical ventilation were randomly selected for mechanical ventilation in NAVA or PSV mode for 120 min, and then another ventilation mode. The differences of man-machine synchronization, respiratory mechanics, gas exchange capacity and hemodynamics in the same patient under the two ventilation modes were compared. Results: there was no significant difference in hemodynamics (HR,CVP) and gas exchange capacity (PaO2,PaCO2,SaO2) between the two models (P 0.05), but there was no significant difference in man-machine synchronization (Trigger delay,Off cycle delay) and respiratory mechanics (PIP,). There was significant difference between NAVA and PSV, in Pmean (P 0.05). Conclusion: for patients with severe traumatic wet lung mechanical ventilation, NAVA mode has the advantages of higher human-computer coordination and stable respiratory mechanics than PSV mode, and has similar safety in hemodynamics and gas exchange ability.
【作者單位】: 天津醫(yī)科大學(xué)一中心臨床學(xué)院ICU;
【基金】:天津市衛(wèi)生局科技基金(2010KY07)
【分類號(hào)】:R655;R563.8
本文編號(hào):2494743
[Abstract]:Objective: to explore the man-machine synchronization, respiratory mechanics and gas exchange ability of neuroelectrical activity-assisted ventilation (NAVA) model compared with traditional pressure-supported ventilation (such as PSV) mode in patients with severe traumatic wet lung (STWL). Hemodynamic differences. Methods: 18 patients with severe traumatic wet lung who needed mechanical ventilation were randomly selected for mechanical ventilation in NAVA or PSV mode for 120 min, and then another ventilation mode. The differences of man-machine synchronization, respiratory mechanics, gas exchange capacity and hemodynamics in the same patient under the two ventilation modes were compared. Results: there was no significant difference in hemodynamics (HR,CVP) and gas exchange capacity (PaO2,PaCO2,SaO2) between the two models (P 0.05), but there was no significant difference in man-machine synchronization (Trigger delay,Off cycle delay) and respiratory mechanics (PIP,). There was significant difference between NAVA and PSV, in Pmean (P 0.05). Conclusion: for patients with severe traumatic wet lung mechanical ventilation, NAVA mode has the advantages of higher human-computer coordination and stable respiratory mechanics than PSV mode, and has similar safety in hemodynamics and gas exchange ability.
【作者單位】: 天津醫(yī)科大學(xué)一中心臨床學(xué)院ICU;
【基金】:天津市衛(wèi)生局科技基金(2010KY07)
【分類號(hào)】:R655;R563.8
【共引文獻(xiàn)】
相關(guān)碩士學(xué)位論文 前1條
1 楊銀芬;通腑瀉熱法輔助治療外科膿毒癥急性肺損傷的臨床研究[D];廣州中醫(yī)藥大學(xué);2008年
【二級(jí)參考文獻(xiàn)】
相關(guān)期刊論文 前1條
1 趙富麗;;適應(yīng)性支持通氣在急性呼吸衰竭治療中的應(yīng)用[J];江蘇醫(yī)藥;2006年10期
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